KOMURO AKIHIKO

コムロアキヒコ | KOMURO AKIHIKO

Affiliation and department：
Job title： Professor
Research theme for competitive and other funds (1)：

2010 - 2015 Elucidation of dynamic pathologies of developmental and neurodegenerative diseases

Papers (17)：

Mineaki Seki, Akihiko Komuro, Tatsuya Ishikawa, Masayuki Takahashi, Masayuki Nashimoto. Genes for tRNA recycling are upregulated in response to infection with Theiler's mouse encephalitis virus. Biochem Biophys Res Commun. 2022. 587. 63-68
Seki M, Komuro A, Takahashi M, Nashimoto M. Transcription from the proximal promoter of ELAC1, a gene for tRNA repair, is upregulated by interferons. Biochem Biophys Res Commun. 2021. 585:. 162-168
Seki M, Komuro A, Ishikawa T, Takahashi M and Nashimoto M. Genes for tRNA recycling are upregulated in response to infections with Theiler’s mouse encephalitis virus. Biorxiv. 2021. 455008
Saida-Tamiya Kana, Tamiya Minoru, Sekiya Genki, Isobe Kazunori, Kitazawa Takaaki, Isaka Nobuhisa, Matsukawa Ayako, Kawahara Kohichi, Komuro Akihiko, Ishiguro Masaji. Structural requirements of cholenamide derivatives as the LXR ligands. Bioorganic & medicinal chemistry letters. 2019. 29. 11. 1330-1335
Masahiko Miyamoto, Akihiko Komuro. PACT is required for MDA5-mediated immunoresponses triggered by Cardiovirus infection via interaction with LGP2. Biochemical and Biophysical Research Communications. 2017. 494. 1-2. 227-233

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Books (2)：

Theilovirus 3C Protease Cleaves the C-Terminal Domain of the Innate Immune RNA Sensor, Melanoma Differentiation-Associated Gene 5, and Impairs Double-Stranded RNA-Mediated IFN Response
American Association of Immunologists 2023
Japanese kampo medicines for the treatment of common diseases: Focus on inflammation Chapter 14: Kampo Medicine for Infectious Disease
Elsevier 2017

Lectures and oral presentations (18)：

Regulation of ATP hydrolysis activity of viral RNA sensors, RIG-I-like receptors by TAR RNA-binging protein
(第45回日本分子生物学会 2022)
Regulation of ATP hydrolysis activity of viral RNA sensors, RIG-I-like receptors by TAR RNA-binging protein
(第62回新潟製菓学懇話会 2022)
Involvement of an RNA silencing factor, TAR-RNA binding protein, in RIG-I-like receptor-mediated antiviral immune responses.
(The 5th Annual Meeting of Living Systems Design Research 2020)
二本鎖RNA結合タンパク質PACTは、LGP2が関与するMDA5ウイルス認識反応の活性化に必要である
(第41回日本分子生物学会 2018)
Function of RNA silencing factors and RIG-I-like receptor LGP2 in anti-viral immune responses against picornavirus infection
(2018)

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Work history (13)：

2017/04 - 現在 Niigata University of Pharmacy and Applied Life Sciences Department of of Pharmacy Professor
2017/04/01 - 現在 Niigata University of Pharmacy and Applied Life Sciences Faculty of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences
2011/04/01 - 2017/03/31 Niigata University of Pharmacy and Applied Life Sciences Faculty of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences
2011/04 - 2017/03 Niigata University of Pharmacy and Applied Life Sciences Department of of Pharmacy Associate Professor
2008/10 - 2010/11 Assistant Professor

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Awards (2)：

Association Membership(s) (4)：

日本薬学会 , 日本免疫学会 , 日本ウイルス学会 , 日本分子生物学会

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