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Rchr

J-GLOBAL ID：201801006114421355 Update date: Jul. 17, 2024

Yamanaka Kazuya

Affiliation and department：

Research field (1)： Applied microbiology

Research theme for competitive and other funds (2)：

2019 - 2022 Identification and characterization of an unprecedented D-peptide degrading enzyme
2016 - 2021 Biosynthetic redesign of small molecules aimed for the concurrent improvements of cell permeability and water solubility

Papers (29)：

Kohei Kaneda, Yamato Takeuchi, Kazuya Yamanaka, Fumihito Hasebe, Chitose Maruyama, Yoshimitsu Hamano. Cell-penetrating activity of a short-chain ε-poly-l-α-lysine. Journal of bioscience and bioengineering. 2024
Fumihito Hasebe, Kazuya Adachi, Kazuya Yamanaka, Tadao Oikawa, Chitose Maruyama, Yoshimitsu Hamano. Constitutive and high gene expression in the diaminopimelate pathway accelerates ε-poly-L-lysine production in Streptomyces albulus. The Journal of antibiotics. 2023. 76. 9. 522-531
Yamato Takeuchi, Kazunori Ushimaru, Kohei Kaneda, Chitose Maruyama, Takashi Ito, Kazuya Yamanaka, Yasushi Ogasawara, Hajime Katano, Yasuo Kato, Tohru Dairi, et al. First direct evidence for direct cell-membrane penetrations of polycationic homopoly(amino acid)s produced by bacteria. Communications Biology. 2022. 5. 1
Takaki Okamoto, Kazuya Yamanaka, Yoshimitsu Hamano, Shingo Nagano, Tomoya Hino. Crystal structure of the adenylation domain from an ε-poly-l-lysine synthetase provides molecular mechanism for substrate specificity. Biochemical and Biophysical Research Communications. 2022. 596. 43-48
Tadao Oikawa, Kouhei Okajima, Kazuya Yamanaka, Shiro Kato. First enzymological characterization of selenocysteine β-lyase from a lactic acid bacterium, Leuconostoc mesenteroides. Amino Acids. 2022

MISC (83)：

岸千紘, 山中一也, 五十嵐雅之, 濱野吉十, 丸山千登勢. Functional analysis of Phenylalanine dihydroxylase found in the resormycin biosynthetic gene cluster. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
岸千紘, 丸山千登勢, 山中一也, 五十嵐雅之, 濱野吉十. 抗生物質resormycin生合成遺伝子群に見出したPhenylalanine水酸化酵素の機能解析. 日本放線菌学会大会講演要旨集. 2021. 35th (CD-ROM)
長谷部文人, 足立和也, 山中一也, 老川典夫, 丸山千登勢, 濱野吉十. 放線菌Streptomyces albulusにおけるL-lysine生合成経路の転写解析. 日本放線菌学会大会講演要旨集. 2021. 35th (CD-ROM)
岸千紘, 丸山千登勢, 山中一也, 五十嵐雅之, 濱野吉十. Functional analysis of Phenylalanine dihydroxylase found in the resormycin biosynthetic gene cluster. 日本生物工学会大会講演要旨集. 2021. 73rd
美馬未紗希, 老川典夫, 山中一也. Effect of the proteasomal gene deletion in an ε-poly-L-lysine producer, Streptomyces albulus. 日本生物工学会大会講演要旨集. 2021. 73rd

Patents (6)：

Lectures and oral presentations (68)：

Exploration of D-peptide degrading enzyme from a poly-D-diaminobutyric acid producer, Streptoalloteichus hindustanus
(2018)
Cloning of the gene coding for novel PLP-independent diaminobutyric acid racemase involved in Poly-D-diaminobutyric acid biosynthesis
(2018)
膜貫通型NRPSであるポリリジン合成酵素のアデニル化ドメインの精製と結晶化
(日本蛋白質科学会年会プログラム・要旨集 2018)
乳酸菌Leuconostoc mesenteroides LK-151のセレン耐性能の評価とセレノシステインβ-リアーゼホモログの機能解析
(日本微量栄養素学会学術集会講演要旨集 2018)
ゲノムマイニングにより見出した新規ホモポリアミノ酸の構造及びその生合成機構の解析
(日本農芸化学会大会講演要旨集(Web) 2018)

Education (3)：

- 2011 論文博士/福井県立大学大学院生物資源学研究科生物資源学専攻
1999 - 2001 Kansai University Graduate School
1996 - 1999 Kansai University Faculty of Engineering Department of Biotechnology

Professional career (1)：

Work history (6)：

2023/04 - 現在 Kansai University
2015/04 - 現在 Kansai University Faculty of Chemistry , Materials and Bioengineering
2013/07 - 2015/03 JNC Corporation Yokohama Research Center
2010/07 - 2013/06 米国カリフォルニア大学サンディエゴ校スクリプス海洋研究所博士研究員
2009/04 - 2010/06 チッソ株式会社(現JNC株式会社) 横浜研究所主任研究員

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Committee career (1)：

2019/06 - 2023/05 The Society for Biotechnology, Japan Editor(Journal of Bioscience and Bioengineering)

Awards (1)：

Association Membership(s) (3)：

SOCIETY FOR ACTINOMYCETES JAPAN , The Society for Biotechnology, Japan , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY

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