Rchr
J-GLOBAL ID：201801007965072538
Update date: Feb. 01, 2024
Yanagitani Kota
ヤナギタニ コウタ | Yanagitani Kota
Affiliation and department：
Job title：
Associate Professor
Research field (1)：
Cell biology
Research keywords (4)：
Protein quality control
, Translational pausing
, Unfolded protein response
, Organelles homeostasis
Research theme for competitive and other funds (7)：
- 2022 - 2026 核-ミトコンドリアキメラ複合体のみなしご解消法
- 2022 - 2025 オルガネラ量ホメオスタシスの根底原理の解明
- 2022 - 2023 タンパク質分泌増強細胞の創出に向けた小胞体量制御原理の解明
- 2019 - 2022 Investigation of the basic principle of organelle-mass homeostasis
- 2012 - 2015 Evocation of the ER stress response by lipid aberrancy
- 2011 - 2012 Investigation of the homeostatic regulation for organelle abundanceby invention of organelle knockdown-technology
- 2007 - 2012 Analyses of the physiological roles of unfolded protein response
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Papers (18)：
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Ashuei Sogawa, Ryota Komori, Kota Yanagitani, Miku Ohfurudono, Akio Tsuru, Koji Kadoi, Yukio Kimata, Hiderou Yoshida, Kenji Kohno. Signal sequence-triage is activated by translocon obstruction sensed by an ER stress sensor IRE1α. Cell structure and function. 2023. 48. 2. 211-221
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柳谷耕太. みなしごタンパク質の品質管理機構. 生化学. 2021. 93. 2. 239-242
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Lilian M Fennell, Carlos Gomez Diaz, Luiza Deszcz, Anoop Kavirayani, David Hoffmann, Kota Yanagitani, Alexander Schleiffer, Karl Mechtler, Astrid Hagelkruys, Josef Penninger, et al. Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling. EMBO J. 2020. 39. 24. e103303
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柳谷耕太. 細胞はいかにして異常なタンパク質に対処するのか?. あいみっく. 2020. 41. 1. 23-25
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Kota Yanagitani, Szymon Juszkiewicz, Ramanujan S. Hegde. UBE2O is a quality control factor for orphans of multiprotein complexes. SCIENCE. 2017. 357. 6350. 472-+
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Books (1)：
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Nascent chain-mediated localization of mRNA on the endoplasmic reticulum as an important step of unfolded protein response.
Springer 2014 ISBN:9784431550518
Lectures and oral presentations (8)：
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Mammalian cells evacuate mitochondrial DNA from mitophagy-dependent degradation under HIF1 activation
(Keystone Symposium “Mitochondrial Dysfunction: From Ultra-Rare Diseases to Aging”, Colorado, USA 2023)
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ミトコンドリア不足に対する細胞応答
(第95回日本生化学会大会 2022)
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Unusual ubiquitination system in quality control of cytosolic proteins
(Ubiquitin Club Meeting 2015)
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小胞体膜上で起こるスプライシングの巧妙な仕組み生化学
(タンパク質の生成と管理』第6回セミナー 2012)
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Ribosomal Stalling Promotes mRNA Splicing on the Endoplasmic Reticulum.
(2011)
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Education (3)：
- 2005 - 2009 Nara Institute of Science and Technology Graduate School of Biological Sciences Department of Cell Biology
- 2003 - 2005 Nara Institute of Science and Technology Graduate School of Biological Sciences Department of Cell Biology
- 1999 - 2003 Shizuoka University Faculty of Science
Professional career (1)：
- 博士(バイオサイエンス) (奈良先端科学技術大学院大学)
Work history (9)：
- 2022/09 - 現在 Osaka University Graduate School of Frontier Biosciences Associate Professor
- 2019/04 - 2022/08 Kyushu University Medical Institute of Bioregulation Associate Professor
- 2018/04 - 2019/03 Nara Institute of Science and Technology, NAIST Institute for Research Initiatives Post-doctoral fellow
- 2016/04 - 2018/03 日本科学技術振興機構 戦略的創造研究推進事業 佐藤ライブ予測制御プロジェクト In vivo オルガネラグループ グループリーダー
- 2016/04 - 2018/03 Advanced Telecommunications Research Institute International, ATR The Thomas N. Sato BioMEC-X Laboratories Group leader
- 2015/03 - 2016/03 MRC Laboratory of Molecular Biology Cell biology division
- 2013/02 - 2015/02 MRC Laboratory of Molecular Biology Cell biology division JSPS Overseas Research Fellow
- 2011/04 - 2013/02 Nara Institute of Science and Technology, NAIST Bioscience division Assistant professor
- 2009/03 - 2011/02 Nara Institute of Science and Technology, NAIST Bioscience division GCOE special post-doctoral fellow
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Awards (8)：
- 2012/08 - Nara Institute of Science and Technology, NAIST -
- 2012/02 - -
- 2011/06 - -
- 2009/11 - -
- 2009/03 - Nara Institute of Science and Technology, NAIST -
- 2008/11 - 特定領域研究“タンパク質の社会” 特定領域研究“タンパク質の社会”全体班会議最優秀ポスター賞
- 2006/09 - Nara Institute of Science and Technology, NAIST -
- 2005/09 - Nara Institute of Science and Technology, NAIST -
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Association Membership(s) (3)：
日本生化学会
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, JAPAN SOCIETY FOR CELL BIOLOGY
