Research field (2):
Pharmaceuticals - health and biochemistry
, Structural biochemistry
Research keywords (4):
構造生物学
, ケミカルバイオロジー
, ヒストン修飾
, エピジェネティクス
Research theme for competitive and other funds (4):
2024 - 2028 リシンアセチル化による後成遺伝情報の発現と継承の仕組みを理解する
2021 - 2024 p300によるヌクレオソームアセチル化の構造基盤
2021 - 2024 治療と根治を両立する革新的マラリア制圧戦略の分子基盤に関する研究開発
2019 - 2021 The recognition mechanism of acetylated nucleosomes by GAS41
Papers (16):
Yuki S Tateishi, Tamasa Araki, Satoru Kawai, Shuhei Koide, Yuko Umeki, Takashi Imai, Yumiko Saito-Nakano, Masaki Kikuchi, Atsushi Iwama, Hajime Hisaeda, et al. Histone H3.3 variant plays a critical role on zygote-to-oocyst development in malaria parasites. Parasitology international. 2024. 102856-102856
Masaki Kikuchi, Shohei Takase, Tsuyoshi Konuma, Kota Noritsugu, Saaya Sekine, Takahisa Ikegami, Akihiro Ito, Takashi Umehara. GAS41 promotes H2A.Z deposition through recognition of the N terminus of histone H3 by the YEATS domain. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 43. e2304103120