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J-GLOBAL ID：201801014634787339 Update date: Jan. 01, 2025

Yuki Masumura

Affiliation and department：

Research field (1)： Cardiology

Research theme for competitive and other funds (2)：

2019 - 2021 Elucidation of the molecular mechanism of genetic disorder in intractable cardiomyopathy using high-content imaging combined with genome editing
2017 - 2019 Verification of novel molecular mechanism of cardiac hypertrophy via regulation of mRNA degradation

Papers (15)：

西尾まゆ, 久米清士, 奥田啓二, 舟田晃, 増村雄喜, 山本隆盛, 清木紳平, 土井泰治, 林亨, 中谷敏, et al. Impact of Hospital Scale and Region on Outcomes in Heart Failure with Preserved Ejection Fraction: Insight from the PURSUIT-HFpEF Registry(タイトル和訳中). 日本循環器学会学術集会抄録集. 2023. 87回. PJ054-2
Tomoka Tabata, Yuki Masumura, Shuichiro Higo, Suzuka Kunimatsu, Satoshi Kameda, Hiroyuki Inoue, Shota Okuno, Shou Ogawa, Seiji Takashima, Mikio Watanabe, et al. Multiplexed measurement of cell type-specific calcium kinetics using high-content image analysis combined with targeted gene disruption. Biochemical and Biophysical Research Communications. 2022
Yasuaki Kohama, Shuichiro Higo, Yuki Masumura, Mikio Shiba, Takumi Kondo, Takamaru Ishizu, Tomoaki Higo, Satoki Nakamura, Satoshi Kameda, Tomoka Tabata, et al. Adeno-associated virus-mediated gene delivery promotes S-phase entry-independent precise targeted integration in cardiomyocytes. Scientific reports. 2020. 10. 1. 15348-15348
Shohei Yashirogi, Takemasa Nagao, Yuya Nishida, Yusuke Takahashi, Tasneem Qaqorh, Issei Yazawa, Toru Katayama, Hidetaka Kioka, Tsubasa S. Matsui, Shigeyoshi Saito, et al. AMPK regulates cell shape of cardiomyocytes by modulating turnover of microtubules through CLIP-170. EMBO Reports. 2020
Masato Shibamoto, Tomoaki Higo, Atsuhiko T Naito, Akito Nakagawa, Tomokazu Sumida, Katsuki Okada, Taku Sakai, Yuki Kuramoto, Toshihiro Yamaguchi, Masamichi Ito, et al. Activation of DNA Damage Response and Cellular Senescence in Cardiac Fibroblasts Limit Cardiac Fibrosis After Myocardial Infarction. International heart journal. 2019. 60. 4. 944-957

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MISC (57)：

西尾まゆ, 久米清士, 奥田啓二, 舟田晃, 増村雄喜, 山本隆盛, 清木紳平, 土井泰治, 林亨, 中谷敏, et al. 左室駆出率が保たれた心不全の転帰に対する病院規模と地域の影響 PURSUIT-HFpEF Registryからの知見(Impact of Hospital Scale and Region on Outcomes in Heart Failure with Preserved Ejection Fraction: Insight from the PURSUIT-HFpEF Registry). 日本循環器学会学術集会抄録集. 2023. 87回. PJ054-2
Masato Shibamoto, Tomoaki Higo, Atsuhiko T. Naito, Akito Nakagawa, Tomokazu Sumida, Katsuki Okada, Taku Sakai, Yuki Kuramoto, Toshihiro Yamaguchi, Masamichi Ito, et al. Activation of DNA Damage Response and Cellular Senescence in Cardiac Fibroblasts Limit Cardiac Fibrosis After Myocardial Infarction (vol 60, pg 944, 2019). INTERNATIONAL HEART JOURNAL. 2021. 62. 1. 220-220
増村雄喜, 肥後修一朗, 朝野仁裕, 北風政史, 坂田泰史, 高島成二. Single Cell Imaging Analysis Clarifies Quantitative Kinetics of RNA in Cardiomyocytes. 日本生化学会大会(Web). 2016. 89th. ROMBUNNO.1T15-04(1P-248) (WEB ONLY)
増村雄喜. 心筋細胞全ゲノム結合プロファイリングを用いた転写因子c-Mycを介するRNA代謝フィードバック. 生産と技術. 2015. 67. 2. 107-107
Yuki Masumura, Shuichiro Higo, Yoshihiro Asano, Yasushi Sakata, Masafumi Kitakaze, Seiji Takashima. Quantitative Genome-wide Binding Profiles Reveals Distinct Kinetics of c-Myc Transcription Factor in Cardiomyocytes. JOURNAL OF CARDIAC FAILURE. 2014. 20. 10. S170-S171

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Lectures and oral presentations (3)：

Rapid Evaluation of Candidate Causal Gene Mutation using High-content Image Analysis Combined with Targeted Gene Disruption
(2018)
Verification of novel molecular mechanism of cardiac hypertrophy via regulation of mRNA degradation
(Cutting Edge Developments in RNA Biology for the Control of Gene Expression 2017)
Genome-wide Binding Profiles of c-Myc and RNA-polymerase II Clarifies c-Myc-mediated Circuit Pathway in RNA Metabolism in Cardiomyocytes
(American Heart Association Scientific Sessions 2014 2014)

Education (2)：

2011 - 2016 大阪大学大学院医学系研究科
1999 - 2005 Osaka University Faculty of Medicine Medical School

Professional career (1)：

医学博士 (大阪大学)

Work history (1)：

2016/09 - 現在医学系研究科循環器内科特任研究員

Awards (6)：

2019/09 - 第3回日本循環器学会基礎研究フォーラム Poster Session Awards
2018/09 - 第2回日本循環器学会基礎研究フォーラム Poster Session Awards
2018/06 - Young Investigator’s Awards 優秀賞
2016/03 - Young Investigator's Award 優秀賞
2015/09 - Poster Session Award Genome-wide Binding Profiles of c-Myc and RNA-polymerase II Clarifies c-Myc-mediated RNA Metabolism in Cardiomyocytes

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