Rchr
J-GLOBAL ID：202301003505811418
Update date: Sep. 23, 2024
Nakano Manabu
ナカノ マナブ | Nakano Manabu
Affiliation and department：
Research field (1)：
Immunology
Research keywords (2)：
細胞外ヌクレオチド
, 好塩基球
Research theme for competitive and other funds (5)：
- 2020 - 2023 細胞外ヌクレオチド受容体に着目したモデル動物を用いたアレルギー新規治療法の検討
- 2019 - 2022 Low-Dose radiation effects on freshwater planarian (Dugesia japonica), in Fukushima
- 2018 - 2020 Regulatory mechanism by extracellular nucleotide receptors for basophil activation
- 2016 - 2019 Comprehensive verification on life-saving mechanism of lethal dose radiation exposed individual by mixed umbilical cord blood transplantation
- 2013 - 2016 Establishment of effective mixed umbilical cord blood transplantation for lethal dose radiation exposure
Papers (17)：
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Kota Sato, Hironori Yoshino, Yoshiaki Sato, Manabu Nakano, Eichi Tsuruga. ΔNp63 Regulates Radioresistance in Human Head and Neck Squamous Carcinoma Cells. Current issues in molecular biology. 2023. 45. 8. 6262-6271
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Hiroyuki Nozaka, Miku Oda, Ami Sasaki, Honoka Harako, Mae Miyazaki, Suzuka Kaga, Niina Sakaiya, Kyouka Kudo, Shou Kimura, Manabu Nakano, et al. The Effect of Data Augmentation in Deep Learning Approach for Peripheral Blood Leukocyte Recognition. Studies in health technology and informatics. 2022. 290. 273-277
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Kosuke Kasai, Manabu Nakano, Masami Ohishi, Toshiya Nakamura, Tomisato Miura. Antimicrobial properties of L-amino acid oxidase: biochemical features and biomedical applications. Applied microbiology and biotechnology. 2021. 105. 12. 4819-4832
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Hironori Yoshino, Yoshiaki Sato, Manabu Nakano. KPNB1 Inhibitor Importazole Reduces Ionizing Radiation-Increased Cell Surface PD-L1 Expression by Modulating Expression and Nuclear Import of IRF1. Current issues in molecular biology. 2021. 43. 1. 153-162
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Naoki Nanashima, Kayo Horie, Mitsuru Chiba, Manabu Nakano, Hayato Maeda, Toshiya Nakamura. Anthocyanin-rich blackcurrant extract inhibits proliferation of the MCF10A healthy human breast epithelial cell line through induction of G0/G1 arrest and apoptosis. Molecular medicine reports. 2017. 16. 5. 6134-6141
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MISC (1)：
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葛西 宏介, 藤田 沙耶花, 石川 孝, 中野 学, 千葉 満, 七島 直樹, 野坂 大喜, 三浦 富智, 中村 敏也. サケ軟骨プロテオグリカンにおける上皮成長因子様作用の証明(Demonstration of Epidermal Growth Factor-like Activity in Salmon Cartilage Proteoglycans). 保健科学研究. 2015. 5. 93-104
Patents (2)：
Lectures and oral presentations (17)：
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Confirmation of the inhibitory effect of P2Y6 receptor antagonist on allergic reaction
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P2Y6 receptor signal by the UDP stimulation increases cAMP and IP1 in human basophils
(JSA/WAO Joint Congress 2020)
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Effect of extracellular nucleotide hydrolysis on IgE-dependent activation of basophils
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好塩基球活性化に対するE-NTPDaseの影響
(第68回日本アレルギー学会学術大会)
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Effect of MRS2578, a P2Y6 receptor inhibitor, on IgE-dependent activation of human basophils
(International GPCR Symposium)
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Education (4)：
- 2013 - 2017 Hirosaki University Graduate School of Health Sciences
- 2004 - 2006 Kobe University
- 2001 - 2004 Tokyo University of Science Faculty of Science, Division 2 Chemistry
- 1997 - 2001 日本医学技術専門学校
Work history (2)：
- 2007/04 - 現在 Hirosaki University Graduate School of Health Sciences
- 2006/04 - 2007/03 Hirosaki University School of Medicine School of Health Sciences
Association Membership(s) (3)：
日本分子生物学会
, 日本アレルギー学会
, 日本免疫学会
