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J-GLOBAL ID：200901049023874803 Update date: Mar. 12, 2025

Nakada Mitsutoshi

ナカダミツトシ | Nakada Mitsutoshi

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Affiliation and department：
Homepage URL (1)： http://neurosurgery.w3.kanazawa-u.ac.jp/

Research field (1)： Neurosurgery

Research keywords (5)： Awake Surgery , Brain Function , Biomarker , Invasion , Brain Tumor

Research theme for competitive and other funds (32)：

2022 - 2026 Analysis of neural networks in brain shallow layer responsible for functional shift aiming at innovation of neurosurgery and neuroscience
2022 - 2026 Molecular basis of blood biomarkers inducing fundamental innovation in glioblastoma medicine
2023 - 2025 脳機能がシフトしうる範囲の解明による新規リハビリテーション指針策定
2022 - 2025 Development of novel therapies for rare malignant brain tumors by drug screening using proprietary tumor cell lines
2020 - 2025 人種間の他者理解脳内ネットワーク解析と覚醒下手術への応用

2021 - 2024 言語機能回復に伴う脳内ネットワーク再組織化の構造的メカニズムの解明

2021 - 2024 膠芽腫の標準治療後病勢を診断する血液バイオマーカーの実用化

2021 - 2023 回復期待度による新規リハビリテーション指針確立に向けた白質神経線維の可塑性の解明

2020 - 2022 Characteristics of brain functional shift accompanied with brain tumor

2019 - 2021 右前頭葉機能の賦活・抑制に関わる新規神経機能ネットワークの解明

2018 - 2021 悪性神経膠腫由来のエクソソームを介したミクログリアによる微小環境整備の解明

2018 - 2021 感情識別機能の術後回復に伴う神経ネットワーク再編成メカニズムの解明

2019 - 2021 革新的プロテオミクスを用いた膠芽腫病勢診断マーカーの探索と診断システムのキット化

2018 - 2020 Determination of the boundary for the right frontal glioma

2016 - 2019 Advanced neurosurgery support system based on fracture prediction and prevention methodologies

2016 - 2018 The glioma convalescence marker development which targeted an RNA-binding factor.

2016 - 2018 Exploration of blood biomarker for glioblastoma

2015 - 2017 Identification of the biomarker in cerebrospinal fluid of glioblastoma by innovative proteomics

2014 - 2017 Observation of micro fluorescence and discrimination of infiltrating brain tumor region using confocal microscope

2014 - 2017 Drag repositioning for malignant glioma targeting glioma stem cells

2014 - 2016 Constraction of basis of glioblastoma treatment targeting for GSK3beta

2014 - 2016 Molecular subclassification of glioblastoma based on the absolute quantitative proteomics

2012 - 2016 Clarification of molecular mechanisms of the blood-brain barrier plasticity based on quantitative targeted absolute proteomics

2012 - 2014 Basic base constraction of malignant glioma therapy targeting for GSK3beta

2012 - 2014 Quantitative targeted absolute proteomics-based diagnostics for personalized cancer chemotherapy

2011 - 2013 Molecular targeted therapy focusing invasion signaling in malignant glioma cell

2009 - 2011 Study on role of membrane-type matrix metalloproteinase-1 in tumor malignancy

2009 - 2010 The identification of invasion associated genes in glioma stem cell

2008 - 2010 Genetic analysis of glioblastoma cancer stem cell with special reference to chronological and spatial change

2007 - 2008 The role of Eph/ephrin in glioma invasion

2002 - 2003 新規細胞外マトリックス分解酵素阻害分子による神経膠芽腫浸潤抑制の試み

2001 - 2002 The analysis of transcription factor and ECM degradation enzyme associated with invasion of glioblastoma

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Papers (351)：

Hirokazu Takami, Masao Matsutani, Tomonari Suzuki, Kazuhiko Takabatake, Takamitsu Fujimaki, Michinari Okamoto, Shigeru Yamaguchi, Masayuki Kanamori, Kenichiro Matsuda, Yukihiko Sonoda, et al. Phase II trial of pathology-based tripartite treatment stratification for patients with CNS germ cell tumors: A long-term follow-up study. Neuro-oncology. 2025. 27. 3. 828-840
Toshiya Ichinose, Yasuo Sasagawa, Kenji Yoshiki, Sho Tamai, Shingo Tanaka, Mitsutoshi Nakada. Cerebrospinal fluid oculorrhea: A rare complication after orbital exenteration for cavernous sinus meningioma with orbital extension and radiation-induced hydrocephalus. Surgical neurology international. 2025. 16. 9-9
Kazuya Futami, Kouichi Misaki, Takehiro Uno, Iku Nambu, Tomoya Kamide, Mitsutoshi Nakada. Characterization of Maximum Wall Shear Stress Points in Unruptured Cerebral Aneurysms Using Four-dimensional Flow Magnetic Resonance Imaging. Clinical neuroradiology. 2024. 34. 4. 899-906
Takehiro Uno, Kouichi Misaki, Taishi Tsutsui, Tomoya Kamide, Mitsutoshi Nakada. Comparative analysis of vascular closure devices for neuroendovascular procedures using Perclose versus Angioseal. Heliyon. 2024. 10. 21. e39975
Takeo Yuno, Yusuke Nakade, Mitsutoshi Nakada, Masashi Kinoshita, Masako Nakata, Shiori Nakagawa, Hiroyasu Oe, Mika Mori, Takashi Wada, Hajime Kanamori. Predicting Postoperative Motor Function After Brain Tumor Resection With Motor Evoked Potential Monitoring Using Decision Tree Analysis. Cureus. 2024. 16. 11. e74155

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MISC (368)：

田中慎吾, 一ノ瀬惇也, 中田光俊. 80歳以上の初発頭蓋内髄膜腫の臨床的特徴と経過. 日本老年脳神経外科学会プログラム・抄録集. 2024. 37th
中田光俊, 一ノ瀬惇也. 片頭痛薬ロメリジンによるグリオーマ幹細胞標的治療の臨床応用へ向けた基礎研究. 金沢大学がん進展制御研究所がんの転移・薬剤耐性に関わる先導的共同研究拠点. 2024. 2023
平井希, 玉井翔, 一ノ瀬惇也, 淑瑠ヘムラサビット, 齋藤紀彦, 中田光俊. EphrinA2はFAKのリン酸化を介して膠芽腫浸潤を促進する. 日本分子脳神経外科学会プログラム・抄録集. 2024. 24th
中田光俊, 中嶋理帆, 木下雅史, 篠原治道. 白質神経線維ネットワークの規則性と脳可塑性-The Rule and Plasticity in Neural Network-特集解剖の泉 : 知識の継承第36回日本微小脳神経外科解剖研究会合同セッション. 脳神経外科ジャーナル / 日本脳神経外科コングレス編. 2023. 32. 8. 474-481
一ノ瀬惇也, 玉井翔, 田中慎吾, 木下雅史, 小林昌彦, 平尾敦, 中田光俊. Identification of lomerizine, a prophylactic drug for migraines, as a potential anti-glioblastoma drug. 日本脳腫瘍学会学術集会プログラム・抄録集. 2023. 41st

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Patents (12)：

医療用器具
がん幹細胞の自己複製阻害剤及びSTAT3のリン酸化阻害剤
医療用リトラクター
バイポーラ鉗子
医療用器具

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Books (1)：

The Handbook of Awake Surgery
2019

Education (2)：

1994 - 1999 Kanazawa University
1988 - 1994 Kanazawa University

Professional career (1)：

博士 (医学) (金沢大学)

Work history (5)：

2014/12 - 現在 Kanazawa University Department of Neurosurgery Professor and Chairman
2007/04 - 2014/11 Department of Neurosurgery Kanazawa University Assistant Professor
2005/04 - Translational Genomics Institute Assistant Professor
2002/10 - 2005/03 Barrow Neurological Institute Postdoctoral fellow
2001/04 - Kanazawa University

Committee career (14)：

2020 - 現在日本脳卒中学会代議員、評議員
2019 - 現在日本脳腫瘍の外科学会理事
2017 - 現在日本awake surgery学会運営委員
2016 - 現在日本癌学会評議員
2015 - 現在日本脳神経外科光線力学学会運営委員

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Awards (11)：

2017/10 - 公益財団法人日本デザイン振興会 2017年度グッドデザイン賞
2013/11 - 金沢市医師会金沢医学館記念医学賞
2011/11 - The Japan Research Foundation for Clinical Pharmacology 4th Annual Clinical Pharmacology Research Award
2010/10 - JUZEN Medical Award
2008 - 臨床薬理研究振興財団研究奨励金

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Association Membership(s) (19)：

日本神経内視鏡学会 , 脳神経外科手術と機器学会 , 日本頭蓋底外科学会 , THE JAPAN SOCIETY FOR CNS COMPUTED IMAGING , 日本awake surgery学会 , 日本脳神経減圧術学会 , THE JAPAN STROKE SOCIETY , 日本脳腫瘍の外科学会 , Japan Photodynamic Neurosurgical Society , JAPAN SOCIETY OF CLINICAL ONCOLOGY , JAPAN EPILEPSY SOCIETY , Society for Neuro-Oncology , American Association for Cancer Research , 日本分子脳神経外科学会 , 日本脳腫瘍学会 , 日本脳腫瘍病理学会 , 日本癌学会 , 日本脳神経外科コングレス , 日本脳神経外科学会

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