Rchr
J-GLOBAL ID:200901052884708344   Update date: Feb. 01, 2024

Ueno Yoshihito

ウエノ ヨシヒト | Ueno Yoshihito
Affiliation and department:
Job title: Professor
Other affiliations (4):
  • Gifu University
  • Gifu University  The United Graduate School of Agricultural Science 
  • Gifu University
  • 東海国立大学機構  One Medicine 創薬シーズ開発・育成研究教育拠点   教授
Homepage URL  (2): http://www1.gifu-u.ac.jp/~biochem/http://www1.gifu-u.ac.jp/%7Ebiochem/
Research field  (3): Molecular biochemistry ,  Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - chemistry and drug development
Research keywords  (14): Organic Chemistry of Nucleic Acids ,  核酸有機化学 ,  miRNA ,  RNAi ,  ヌクレオチド ,  RNA ,  ヌクレオシド ,  核酸医薬 ,  核酸 ,  アンチセンス ,  siRNA ,  オリゴヌクレオチド ,  遺伝子 ,  DNA
Research theme for competitive and other funds  (22):
  • 2020 - 2024 Basic study on essential understanding and innovative application of the lipid metabolism improvement peptide derived from food protein
  • 2017 - 2020 Fundamental study on the lipid lowering peptides derived from food proteins
  • 2014 - 2017 Discovery of Innovative lipid lowering peptides by targetting the bio-molecule and Creation of novel screening technology
  • 2016 - 2017 組織特異的送達能を有するコンジュゲートsiRNAの創成
  • 2013 - 2016 Development of the tumor marker detection method by RNA aptamer
Show all
Papers (176):
  • Hitotaka Sato, Akash Chandela, Yoshihito Ueno. Synthesis and characterization of novel (S)-5'-C-aminopropyl-2'-fluorouridine modified oligonucleotides as therapeutic siRNAs. Bioorganic & medicinal chemistry. 2023. 87. 117317-117317
  • Yujun Zhou, Shuichi Sakamoto, Yoshihito Ueno. Antisense Gapmers with LNA-Wings and (S)-5'-C-Aminopropyl-2'-arabinofluoro-nucleosides Could Efficiently Suppress the Expression of KNTC2. Molecules (Basel, Switzerland). 2022. 27. 21
  • Akash Chandela, Hiroki Ueda, Yoshihito Ueno. Synthesis of 4′- C -(Aminoethyl)thymidine and 4′- C -[( N -Methyl)aminoethyl] Thymidine Nucleosides to Enhance DNA Stability. Current Protocols. 2022. 2. 9. e501
  • Yuki Katsuzaki, Ryo Tsukimura, Akash Chandela, Tokuhiro Chano, Yoshihito Ueno. 4′- <i>C</i> -Aminoethoxy-Modified DNAs Exhibit Increased Nuclease Resistance, Sustained RNase H Activity, and Inhibition of <i>KRAS</i> Gene Expression. Chemistry & Biodiversity. 2022. 19. 8. e202200125
  • Ryutaro Yoshikawa, Atsushi Maeda, Yoshihito Ueno, Hiroki Sakai, Shintaro Kimura, Tomohiro Sawadaishi, Satoru Kohgo, Kohei Yamada, Takashi Mori. Intraperitoneal administration of synthetic microRNA-214 elicits tumor suppression in an intraperitoneal dissemination mouse model of canine hemangiosarcoma. Veterinary research communications. 2022. 46. 2. 447-457
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MISC (55):
more...
Patents (19):
Books (5):
  • 人工核酸によるアンチジーン法への展開 三重らせん形成による遺伝子治療
    2003
  • ポリアミン修飾オリゴヌクレオチドの合成とアンチセンス, アンチジーン分子としての性質
    2003
  • Development of new radical reactions with a vinylsilyl group and their application to the synthesis of branched-chain sugar nucleosides
    2002
  • Development of new radical reactions with a vinylsilyl group and their application to the synthesis of branched-chain sugar nucleosides
    Recent Advances in Nucleosides:Chemistry and Chemotherapy 2002
  • ヌクレオペプチドの化学合成
    1995
Education (2):
  • 1987 - 1992 東京工業大学大学院 総合理工学研究科 生命化学専攻
  • 1983 - 1987 Tokyo University of Science
Professional career (3):
  • (BLANK) (Tokyo Institute of Technology)
  • 修士(理学) (東京工業大学)
  • 学士(理学) (東京理科大学)
Work history (5):
  • 2013/04 - 現在 Gifu University
  • 2011/04 - 2013/03 Gifu University
  • 2001/04 - 2011/03 Gifu University Faculty of Engineering, Department of Biomolecular Science
  • 1993/06 - 2001/03 Hokkaido University Faculty of Pharmaceutical Sciences
  • 1992/04 - 1993/05 科学技術庁 (理化学研究所) 基礎科学特別研究員
Committee career (1):
  • 2015/04 - 現在 日本核酸医薬学会 評議員
Association Membership(s) (4):
日本核酸化学会 ,  日本核酸医薬学会 ,  日本農芸化学会 ,  日本化学会
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