Rchr
J-GLOBAL ID：200901053873010589
Update date: Apr. 04, 2025 Ogura Hiroshi
オグラ ヒロシ | Ogura Hiroshi
Associate Professor
Other affiliations (1)： - Osaka University
Graduate School of Medicine Division of Medicine
Associate Professor
Research field (2)：
Emergency medicine
, General surgery, pediatric surgery
Research keywords (4)：
infection medicine
, intensive care medicine
, acute medicine
, 救急医学
Research theme for competitive and other funds (67)： - 2024 - 2027 Development of a machine learning model for early pediction of septic coagulopathy
- 2024 - 2027 頭部外傷患者に対する新規抗酸化物質を用いた神経機能回復に関する研究
- 2024 - 2027 ミトコンドリア移植による外傷性脳損傷後の神経機能回復に関する研究
- 2024 - 2027 敗血症におけるエピジェネティクス制御因子のメカニズム解明
- 2024 - 2026 侵襲時再生治療に関する新規制御因子の解明:ゲノム・エピゲノム統合解析
- 2023 - 2026 侵襲時再生治療に関する新規制御因子の解明:ゲノム・エピゲノム統合解析
- 2023 - 2026 免疫応答バランスからみた熱傷後の免疫不全メカニズムに関する統合的解析
- 2023 - 2026 Development of a new method for evaluating gut microbiota that can be evaluated in a simple, low-cost, and short time
- 2022 - 2025 Analysis of gut barrier function and immunity via gut microbiota and establishment of gut microbiota reconstruction therapy in critically ill condition
- 2022 - 2025 網羅的生体分子情報に基づく重症熱傷病態の中心的分子解明と新規治療薬開発
- 2022 - 2025 Immunomolecular pathogenesis of systemic and local lung immunity in ARDS based on integrated analysis
- 2022 - 2025 脂肪細胞による全身性炎症反応制御:オートファジーとアディポカイン産生
- 2022 - 2025 網羅的分子生体情報を用いた頭部外傷患者に対する新たな治療戦略の構築
- 2021 - 2024 neuroprotective effects after traumatic brain injury by enteric hydrogen generation from Si-based agent
- 2021 - 2024 シングル細胞シークエンスを用いた敗血症における免疫抑制病態の解明と新規治療法開発
- 2021 - 2024 トランスクリプトームを用いた心停止の分子ネットワーク病態の解明と神経予後予測
- 2021 - 2024 ナノポア技術と機械学習を用いた新たな微生物迅速診断検査系の確立
- 2020 - 2023 The association between gut microbiome and host immunity focused on regulatory T cell in patients with critical illness
- 2020 - 2023 敗血症の炎症最適化のためのマーカーと分子病態分類の解明:HIVEP1の臨床応用
- 2020 - 2023 Profiling of circulating micro RNA expression in patients with sepsis
- 2021 - 2023 Development and clinical application of novel biomarkers of molecular pathogenesis using comprehensive gene/protein expression analysis in patients with novel coronavirus infection (COVID-19)
- 2019 - 2022 Trauma-specific memory-like regulatory T-cell responses and fundamental research for clinical translation
- 2019 - 2022 New developments in regenerative therapy for critical illness: the role of novel inflammatory amplification mechanisms.
- 2019 - 2022 重症病態での腸内細菌叢を介した免疫システム解明と腸内細菌叢再構築のための治療戦略
- 2019 - 2022 重症熱傷におけるグリコカリックスからみた血管内皮障害メカニズム解明と制御法の確立
- 2017 - 2022 Reconsideration of active therapeutics of septic enephalopathy by non-invasive methods focusing on molecular mechanism
- 2018 - 2021 Myeloid-derived suppressor cells infiltrate the brain and suppress neuroinflammation in a mouse model of focal traumatic brain injury
- 2017 - 2020 Randomized controlled trial of the effect of low carbohydrate and high fat diet on blood glucose variation in critically ill patients
- 2016 - 2020 A novel approach for diagnosis of meningitis and encephalitis using metagenomic sequencing
- 2016 - 2019 A novel development of regenerative therapy following acute systemic inflammatory response syndrome: the effects of transplantation of bone marrow-derived mononuclear cells and new rejuvenation factor
- 2016 - 2019 Citrullinated histon H3 for control of ciritical illness
- 2016 - 2019 Elucidation of mechanisms between endothelial injury and host immune response in severe trauma patients
- 2016 - 2019 Explanatory research of consciousness related substances in iPS cell-derived brain microvascular endothelial cell models
- 2015 - 2018 elucidation of the brain circulation during prehospital resuscitation
- 2015 - 2018 Establishment of methods for immune response analysis of lymphocytes and neutrophils against sepsis and trauma
- 2015 - 2018 A novel strategy for organ dysfunctions following systemic inflammatory response syndrome: the effect of new rejuvenation factor GDF11
- 2014 - 2017 The analysis of the gut microbiota change in severe emergency patients via high-throughput DNA sequencing
- 2013 - 2017 New strategy for critically ill patients by control of NETs
- 2013 - 2016 Regenerative therapy following severe insults: Establishment of cell transplantation and elucidation of immunologic response
- 2012 - 2015 Elucidation of the brain circulation during resuscitation.
- 2012 - 2015 A novel strategy for heat stroke: targeted therapy for free nucleotides
- 2012 - 2015 Establishment of synbiotic therapy in severe sepsis
- 2012 - 2014 Development of a novel strategy for heatstroke via the cholinergic anti-inflammatory pathway
- 2010 - 2014 The development of cell transplantation therapy against sepsis-associated multiple organ dysfunction targeted at endogenous stem cell function.
- 2010 - 2013 Regenerative therapy following severe insults : Establishment of cell transplantation in the blood
- 2010 - 2013 侵襲期低栄養患者に関するリスク評価及び病態解析
- 2009 - 2011 The effects of"Preemptive Infection Control" in critical care center
- 2009 - 2011 A novel strategy for heat stroke: Transplantation of mesenchymal stem cells
- 2007 - 2009 Regenerative response to insults : a novel strategy based on endothelial regeneration
- 2007 - 2009 Pathophysiological analysis for patients with anoxic coma after cardiopulmonary arrest.
- 2007 - 2009 Activation of endogenous neural stem cells using choroid plexus epithelial cells aimed at a new therapy for central nervous system injury
- 2006 - 2008 白血球のアクアポリンを介した全身性炎症反応の制御に関する研究
- 2006 - 2007 クラッシュ症候群における病態と治療に関する研究
- 2005 - 2007 The study on new artificial red blood cells (encapsulation Hb) at the shock
- 2005 - 2007 Gut flora and synbiotics therapy in patients with severe SIRS
- 2004 - 2006 Mechanisms of organ failure and abnormal oxygen metabolism during sepsis
- 2004 - 2006 ラット肺微少循環機能のリアルタイム計測技術の開発と応用
- 2003 - 2005 Immune response to severe insults: reaction through Toll-like receptors
- 2003 - 2005 Research on physiological responses in the acute phase of anoxic coma patients
- 2002 - 2004 Stress responses and leukocyte functions in sepsis
- 2001 - 2003 Telemedical support of emergency medicine using real-time telecommunication system.
- 2001 - 2003 脳死後の肺障害発生機序の解明と肺機能温存法開発に関する研究
- 2000 - 2002 Platelet-microparticles as a carrier of chemical mediators inducing remote organ failure
- 2000 - 2002 生体顕微鏡を用いた肺微小循環の可視化解析に関する研究
- 1999 - 2001 Investigation of the mechanism in multiple organ failure and the new approach by regulating leukocyte function
- 1998 - 2000 Elucidation of the mechanisms of cross-talk between the neurological, endocrine, and immune systems in the biological response to physical insults
- 1998 - 1999 侵襲時の多核白血球(PMNL)機能に関する総括的研究
Show all
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Ryota Nukiwa, Sayaka Oda, Hisatake Matsumoto, Mohamad Al Kadi, Shuhei Murao, Tsunehiro Matsubara, Shunichiro Nakao, Daisuke Okuzaki, Hiroshi Ogura, Jun Oda. Changes in gene expression in healthcare workers during night shifts: implications for immune response and health risks. Journal of intensive care. 2025. 13. 1. 14-14
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Satoshi Gando, Takeshi Wada, Kazuma Yamakawa, Toshikazu Abe, Seitato Fujishima, Shigeki Kushimoto, Toshihiko Mayumi, Hiroshi Ogura, Daizoh Saitoh, Atsushi Shiraishi, et al. Utility of sepsis-induced coagulopathy among disseminated intravascular coagulation diagnostic criteria: A multicenter retrospective validation study. Thrombosis and haemostasis. 2025
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Sayaka Oda, Hisatake Matsumoto, Yuki Togami, Jumpei Yoshimura, Hiroshi Ito, Shinya Onishi, Arisa Muratsu, Yumi Mitsuyama, Daisuke Okuzaki, Hiroshi Ogura, et al. mRNA-miRNA integration analysis of T-cell exhaustion in sepsis from community-acquired pneumonia. Acute medicine & surgery. 2025. 12. 1. e70054
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Eri Kobayashi, Atsushi Shiraishi, Toshiyuki Karumai, Yoshiro Hayashi, Toshikazu Abe, Hiroshi Ogura, Kushimoto Shigeki, Satoshi Gando, Kohji Okamoto, Yutaka Umemura, et al. Carbapenem Usage in the Initial Antibiotic Therapy of Sepsis in Japanese Intensive Care Units. Cureus. 2025. 17. 1. e77271
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Takeshi Nishida, Jotaro Tachino, Yoshinori Yokono, Takeshi Ebihara, Hisatake Matsumoto, Hiroshi Ogura, Kansuke Kido, Koki Muto, Masako Kurashige, Jun Oda. Severe acute respiratory failure induced by TMP-SMX in a healthy adult with HLA-B*07:02 and HLA-C*07:02 alleles. QJM : monthly journal of the Association of Physicians. 2024
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島崎淳也, 島崎淳也, 松本寿健, 小倉裕司, 嶋津岳士. ラットモデルを用いたクラッシュ症候群の病態解明. 日本急性血液浄化学会雑誌. 2024. 15. Supplement
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蛯原健, 松本寿健, 戸上由貴, 戸上由貴, 松浦裕司, 小倉裕司, 織田順. COVID-19と細菌性敗血症における補体活性化の比較. 日本集中治療医学会学術集会(Web). 2024. 51st
ｍore...- Reversible MR findings of hemolytic uremic syndrome with mild encepholopathy.
Am. J. Neuroradiol 1998
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脈叢上衣細胞を用いた内在性神経幹細胞の賦活化-中枢神経損傷治療応用を目指して-
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蘇生後低酸素脳症患者の急性期病態の解明と治療法開発に関する研究
2007 -
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感染侵襲時の酸素代謝異常・臓器不全発症機転解明とその治療に関する研究
2006 -
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感染侵襲時の酸素代謝異常・臓器不全発症機転解明とその治療に関する研究
2004 -
日本外科代謝栄養学会
, 日本外傷学会
, 日本熱傷学会
, 日本外科学会
, 日本救急医学会
, 日本災害医学会
, 日本集中治療医学会
, 日本感染症学会
, AAST
, 日本外科感染症学会
, 日本炎症再生学会
, 臨床救急医学会
, 日本臨床栄養学会
