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J-GLOBAL ID：200901055383722257 Update date: Mar. 27, 2025

Iino Ryota

イイノリョウタ | Iino Ryota

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Affiliation and department：
Job title： Professor
Other affiliations (1)：

The Graduate University for Advanced Studies Professor

Homepage URL (1)： https://groups.ims.ac.jp/organization/iino_g/index.html

Research field (3)： Biophysics , Nanobioscience , Molecular biochemistry

Research keywords (6)： Molecular Motors , Motor Proteins , Artificial molecular motors , Single-molecule Analysis , Protein Engineering , DNA nanotechnology

Research theme for competitive and other funds (42)：

2024 - 2027 ナトリウムイオン輸送性回転イオンポンプV-ATPaseのエネルギー変換機構の解明
2023 - 2025 生体分子モーターに匹敵する速さで動き制御可能な人工分子モーターをつくる
2021 - 2024 Verification of "rotation model" of bacterial flagellar rotor with single-molecule analysis
2018 - 2023 生体・人工発動分子によるエネルギー変換過程の1分子計測法の開発
2020 - 2022 生体機能を凌駕するサイボーグ型分子機械の構築

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Papers (159)：

Akihiro Otomo, Lucy Gao Hui Zhu, Yasuko Okuni, Mayuko Yamamoto, Ryota Iino. ATP synthesis of Enterococcus hirae V-ATPase driven by sodium motive force. The Journal of Biological Chemistry. 2025. 108422-108422
Takanori Harashima, Akihiro Otomo, Ryota Iino. Rational engineering of DNA-nanoparticle motor with high speed and processivity comparable to motor proteins. Nature Communications. 2025
Kano Suzuki, Yoshiyuki Goto, Akihiro Otomo, Kouki Shimizu, Shohei Abe, Katsuhiko Moriyama, Satoshi Yasuda, Yusuke Hashimoto, Jun Kurushima, Sho Mikuriya, et al. Na+-V-ATPase inhibitor curbs VRE growth and unveils Na+ pathway structure. Nature Structural & Molecular Biology. 2024
Akihiro Otomo, Jared Wiemann, Swagata Bhattacharyya, Mayuko Yamamoto, Yan Yu, Ryota Iino. Visualizing Single V-ATPase Rotation Using Janus Nanoparticles. Nano Letters. 2024
Takanori Harashima, Akihiro Otomo, Ryota Iino. Mechanism-based design of DNA-nanoparticle motor with high speed and processivity comparable to motor proteins. bioRxiv. 2024

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MISC (79)：

David A. Leigh, 飯野亮太, 金原数. インタビュー:分子マシン研究をリードするDavid A. Leigh博士. 現代化学. 2023. 28-32
金原数, 飯野亮太, 竹内正之, 前多裕介. はたらく分子マシン:ナノの世界のエネルギー変換へ. 現代化学. 2022. 46-50
飯野亮太. 生体分子モーターの予想外の動きを観る. 現代化学. 2021. 19-23
Ryota IINO. 生きものが機械でもいいじゃない. Seibutsu Butsuri. 2021. 61. 2. 77-077
安藤潤, 飯野亮太. 銀, 金, 銀金合金ナノ粒子の光散乱を利用したマルチカラー生体1分子追跡. フォトニクスニュース. 2021. 6. 132-136

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Patents (9)：

タンパク質、ポリヌクレオチド、組換えベクター、形質転換体、ポリエチレンテレフタレート分解用組成物、及びリサイクル品の製造方法
Detector and detection method
Method for inspecting susceptibility of bacteria or fungi to antimicrobial drug and system for use in the same
Bead trapping method and method for detecting target molecule
Fluorescently labeled fusion protein for assaying adenosine triphosphate

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Lectures and oral presentations (166)：

TBA
(Telluride Workshop on Protein Dynamics 2025)
Rational engineering of high performance artificial molecular motors
(20th Asian Chemical Congress (20ACC) 2025)
Rational engineering for high-performance DNA artificial molecular motor
(Workshop "Redesign of molecular machines", The 25th Annual Meeting of the Protein Science Society of Japan 2025)
Optical tracking and rational engineering of DNA-nanoparticle artificial motor with high speed and processivity comparable to motor proteins
(Workshop "Enabling Technologies: From Atoms, Optics, and Beyond", 65th Annual Meeting of the Biophysical Society 2025)
Engineering Biological and Artificial Molecular Motors
(The 1st International Symposium on Molecular Materials for Future (1st ISMMF) 2025)

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Education (3)：

1997 - 2000 Nagoya Univeristy Graduate School of Science Department of Biological Science
1995 - 1997 Kyoto Univeristy Graduate School of Engineering Department of Synthetic Chemistry and Biological Chemistry
1991 - 1995 Kyoto Univeristy Faculty of Engineering Department of Polymer Chemistry

Professional career (1)：

Ph. D. (Nagoya University)

Work history (14)：

2023/04 - 現在 The Graduate University for Advanced Studies Graduate Institute for Advanced Studies Professor
2023/04 - 現在 National Institutes of Natural Sciences Headquarters for Co-Creation Strategy Professor
2018/04 - 現在 National Institutes of Natural Sciences Institute for Molecular Science Director
2014/06 - 現在 National Institutes of Natural Sciences Institute for Molecular Science Professor
2018/04 - 2023/03 National Institutes of Natural Sciences International Research Collaboration Center Professor

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Committee career (16)：

2025/02 - 現在 Biophysical Society, USA Council Member
2024/01 - 現在 The Biophysical Society of Japan Biophysics and Physicobiology (BPPB), Editorial Board Member
2020/01 - 現在 Biophysical Society, USA Biophysical Journal, Editorial Board Member
2024/04 - 2026/03 東京大学物性研究所外来研究員等委員会委員
2023/01 - 2023/11 日本生物物理学会分野別専門委員(A-13. モータータンパク質)

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Awards (1)：

2012/09 - Emerging Investigator, Lab on a Chip, The Royal Society of Chemistry

Association Membership(s) (4)：

American Chemical Society , American Society for Biochemistry and Molecular Biology , Biophysical Society , The Biophysical Society of Japan

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