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J-GLOBAL ID：200902180606255160   Reference number：98A0951075

Defects of cholecystokinin (CCK)-A receptor gene expression and CCK-A receptor-mediated biological functions in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.

Otsuka Long-Evans Tokushima Fatty(OLETF)ラットにおけるコレシストキニン(CCK)-A受容体遺伝子発現の欠損とCCK-A受容体を介する生物学的機能

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Author (9)： NAKAMURA H (Univ. Occupational and Environmental Health, Kitakyushu, JPN) ,  KIHARA Y (Univ. Occupational and Environmental Health, Kitakyushu, JPN) ,  TASHIRO M (Univ. Occupational and Environmental Health, Kitakyushu, JPN) ,  KANAGAWA K (Univ. Occupational and Environmental Health, Kitakyushu, JPN) ,  SHIROHARA H (Univ. Occupational and Environmental Health, Kitakyushu, JPN) ,  YAMAMOTO M (Univ. Occupational and Environmental Health, Kitakyushu, JPN) ,  YOSHIKAWA H (Univ. Occupational and Environmental Health, Kitakyushu, JPN) ,  FUKUMITSU K (Univ. Occupational and Environmental Health, Kitakyushu, JPN) ,  OTSUKI M (Univ. Occupational and Environmental Health, Kitakyushu, JPN)
Material： Journal of Gastroenterology  (J Gastroenterol)
Volume： 33  Issue： 5  Page： 702-709  Publication year： Oct. 1998 
JST Material Number： Z0748A  ISSN： 0944-1174  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： *cholecystokinin ,...
Semi thesaurus term： CCK-A受容体 ,...

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JST classification (3)： Animal metabolism and nutrition in general  (EJ02031R) ,  Molecular genetics in general  (EC02010J) ,  Hormones,cytokines,bioactive peptides in general  (EB08010W)

Reference (33)：

• KAWANO, K. Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain. Diabetes. 1992, 41, 1422-1428
• FUNAKOSHI, A. Little or no expression of the cholecystokinin-A receptor gene in the pancreas of diabetic rats (Otsuka Long-Evans Tokushima Fatty = OLETF rats). Biochem Biophys Res Commun. 1994, 199, 482-488
• TACHIBANA, I. Defect in pancreatic exocrine and endocrine response to CCK in genetically diabetic OLETF rats. Am J Physiol. 1996, 270, G730-G737
• OTSUKI, M. Loss of sensitivity to cholecystokinin stimulation of isolated pancreatic acini from genetically diabetic rats. Am J Physiol. 1995, 268, E531-E536
• LIDDLE, RA. Integrated action of cholecystokinin on the gastrointestinal tract : Use of the cholecystokinin bioassay. Gastroenterol Clin North Am. 1989, 18, 735-756

Terms in the title (7)： ラット ,  コレシストキニン ,  CCK ,  受容体遺伝子 ,  欠損 ,  受容体 ,  生物学的機能