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J-GLOBAL ID：200902208820291230   Reference number：08A0559653

Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by β-catenin/TCF

肝細胞癌で過剰発現する遺伝子NOTUMのヒトホモログはβカテニン/TCFにより転写的に制御される

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Author (18)： TORISU Yuichi (Univ. Tokyo, Tokyo) ,  TORISU Yuichi (Jikei Univ. School of Medicine, Tokyo) ,  WATANABE Akira (Univ. Tokyo, Tokyo) ,  NONAKA Aya (Univ. Tokyo, Tokyo) ,  MIDORIKAWA Yutaka (Univ. Tokyo, Tokyo) ,  MIDORIKAWA Yutaka (Univ. Tokyo Hospital, Tokyo) ,  MIDORIKAWA Yutaka (Teikyo Univ. School of Medicine, Kanagawa) ,  MAKUUCHI Masatoshi (Univ. Tokyo Hospital, Tokyo) ,  SHIMAMURA Takahiro (Univ. Tokyo, Tokyo) ,  SHIMAMURA Takahiro (Hamamatsu Univ. School of Medicine, Shizuoka) ,  SUGIMURA Haruhiko (Hamamatsu Univ. School of Medicine, Shizuoka) ,  NIIDA Atsushi (Univ. Tokyo, Tokyo) ,  AKIYAMA Tetsu (Univ. Tokyo, Tokyo) ,  IWANARI Hiroko (Univ. Tokyo, Tokyo) ,  IWANARI Hiroko (Perseus Proteomics, Tokyo, JPN) ,  KODAMA Tatsuhiko (Univ. Tokyo, Tokyo) ,  ZENIYA Mikio (Jikei Univ. School of Medicine, Tokyo) ,  ABURATANI Hiroyuki (Univ. Tokyo, Tokyo)
Material： Cancer Science  (Cancer Sci)
Volume： 99  Issue： 6  Page： 1139-1146  Publication year： Jun. 2008 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： cellular signal transduction ,...

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JST classification (2)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Basic oncology in general  (GE02010R)

Reference (38)：

• EL-SERAG, HB. Rising incidence of hepatocellular carcinoma in the United States. N Engl J Med. 1999, 340, 745-750
• LLOVET, JM. Hepatocellular carcinoma. Lancet. 2003, 362, 1907-1917
• BREUHAHN, K. Dysregulation of growth factor signaling in human hepatocellular carcinoma. Oncogene. 2006, 25, 3787-3800
• PEIFER, M. Wnt signaling in oncogenesis and embryogenesis-a look outside the nucleus. Science. 2000, 287, 1606-1609
• SMALLEY, MJ. Wnt signalling in mammalian development and cancer. Cancer Metastasis Rev. 1999, 18, 215-230

Terms in the title (8)： 肝細胞癌 ,  過剰発現 ,  遺伝子 ,  ヒト ,  ホモログ ,  βカテニン ,  TCF ,  転写