Art

J-GLOBAL ID：201302255144937247   Reference number：13A1942373

Recombinant proteins produced into yolk of genetically manipulated chickens are partly sialylated in N-glycan

遺伝的に操作されたニワトリの卵黄内で産生された組換蛋白質はN-グリカンにて部分的にシアリル化されている

Author (12)： YOSHIDA Kazuhiro (Nagoya Univ., Dep. of Biotechnology, Graduate School of Engineering, Furo-cho, Chikusa-ku, 464-8603, Nagoya, JPN) ,  OKUZAKI Yuya (Nagoya Univ., Dep. of Biotechnology, Graduate School of Engineering, Furo-cho, Chikusa-ku, 464-8603, Nagoya, JPN) ,  NISHIJIMA Ken-Ichi (Nagoya Univ., Dep. of Biotechnology, Graduate School of Engineering, Furo-cho, Chikusa-ku, 464-8603, Nagoya, JPN) ,  KYOGOKU Kenji (Kaneka Corp., Frontier Biochemical and Medical Res. Laboratories, 1-8, Miyamae-machi, Takasago-cho, 676-8688 ...) ,  YAMASHITA Takashi (Kaneka Corp., Frontier Biochemical and Medical Res. Laboratories, 1-8, Miyamae-machi, Takasago-cho, 676-8688 ...) ,  KAWABE Yoshinori (Nagoya Univ., Dep. of Biotechnology, Graduate School of Engineering, Furo-cho, Chikusa-ku, 464-8603, Nagoya, JPN) ,  KAWABE Yoshinori (Kyushu Univ., Dep. of Chemical Engineering, Graduate School of Engineering, 744 Motooka, Nishi-ku, 819-0395, Fukuoka ...) ,  MOTONO Makoto (Nagoya Univ., Dep. of Biotechnology, Graduate School of Engineering, Furo-cho, Chikusa-ku, 464-8603, Nagoya, JPN) ,  MOTONO Makoto (Kyoto Univ., Lab. of Neuronal Regeneration, Dep. of Clinical Application, Center for iPS Cell Res. and Application ...) ,  KAMIHIRA Masamichi (Nagoya Univ., Dep. of Biotechnology, Graduate School of Engineering, Furo-cho, Chikusa-ku, 464-8603, Nagoya, JPN) ,  KAMIHIRA Masamichi (Kyushu Univ., Dep. of Chemical Engineering, Graduate School of Engineering, 744 Motooka, Nishi-ku, 819-0395, Fukuoka ...) ,  IIJIMA Shinji (Nagoya Univ., Dep. of Biotechnology, Graduate School of Engineering, Furo-cho, Chikusa-ku, 464-8603, Nagoya, JPN)
Material： Cytotechnology
Volume： 65  Issue： 6  Page： 985-992  Publication year： Dec. 2013 
JST Material Number： T0921A  ISSN： 0920-9069  CODEN： CYTOER  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *transgenic animal ,  *Gallus gallus domesticus ,  transformation ,  gene introduction ,  *yolk ,  recombinant protein ,  glycoside ,  polysaccharide ,  *Glycosylation ,  *drug ,  Biotechnology ,  biological activity ,  *protein complex ,  *transgenic chicken ,  N-glycan ,  *sialylation ,  *biotechnology-based drugs ,  *organism ,  *Phasianidae
Semi thesaurus term： *TNFR/Fc蛋白質 ,  *scFv/Fc蛋白質

JST classification (4)： Production and application of antigens,antibodies,complements  (ED04030W) ,  Gene expression  (EC02040Q) ,  Animal biochemistry  (EJ01050P) ,  Basic research of immunotherapeutic agents and blood preparations  (GW22010D)

Terms in the title (6)： 遺伝 ,  ニワトリ ,  卵黄 ,  組換蛋白質 ,  N-グリカン ,  シアリル化