TSUKIYAMA Tomoyuki

ツキヤマトモユキ | TSUKIYAMA Tomoyuki

Affiliation and department：
Other affiliations (1)：

Homepage URL (1)： https://ameblo.jp/regenerative-kyoto/

Research field (4)： Zoological sciences , Animal production science , Laboratory animal science , Developmental biology

Research keywords (9)：遺伝子改変 , 大動物 , カニクイザル , ゲノム編集 , Reproductive Biology , Stem cells , ES cells , iPS cells , reprogramming

Research theme for competitive and other funds (16)：

2022 - 2027 Elucidating the pathogenesis of and development of therapeutic strategies against the neuropsychiatric disorders in the primate models by utilizing the gene introduction and manipulation technologies
2023 - 2026 Primate Nephrology: analyzing primate-specific repair mechanisms of renal injury
2021 - 2026 Spatio-temporal variabilities and robustness in pre-implantation mammalian development
2023 - 2025 Partial reprogramming of trophoblast stem cells to improve placental function
2022 - 2025 遺伝子改変動物作出におけるモザイク性の解消

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Papers (38)：

Akira Sato, Tomoyuki Tsukiyama, Masahiro Komeno, Chizuru Iwatani, Hideaki Tsuchiya, Ikuo Kawamoto, Mitsuru Murase, Takahiro Nakagawa, Iori Itagaki, Yasunari Seita, et al. Generation of a familial hypercholesterolemia model in non-human primate. Scientific Reports. 2023. 13. 1
Satsuki Takashima, Eiichi Okamura, Yusuke Ichiyama, Kiyoto Nishi, Akio Shimizu, Chisato Watanabe, Masanaga Muto, Shoma Matsumoto, Setsuko Tsukiyama-Fujii, Tomoyuki Tsukiyama, et al. Null mutation of exocyst complex component 3-like does not affect vascular development in mice. Experimental animals. 2023
Prachiti Moghe, Roman Belousov, Takafumi Ichikawa, Chizuru Iwatani, Tomoyuki Tsukiyama, François Graner, Anna Erzberger, Takashi Hiiragi. Apical-driven cell sorting optimised for tissue geometry ensures robust patterning. 2023
Sayuri Gyobu-Motani, Yukihiro Yabuta, Ken Mizuta, Yoshitaka Katou, Ikuhiro Okamoto, Masanori Kawasaki, Ayaka Kitamura, Tomoyuki Tsukiyama, Chizuru Iwatani, Hideaki Tsuchiya, et al. Induction of fetal meiotic oocytes from embryonic stem cells in cynomolgus monkeys. The EMBO Journal. 2023. 42. 9. e112962
Dimitri Fabrèges, Bernat Corominas Murtra, Prachiti Moghe, Alison Kickuth, Takafumi Ichikawa, Chizuru Iwatani, Tomoyuki Tsukiyama, Nathalie Daniel, Julie Gering, Anniek Stokkermans, et al. Temporal variability and cell mechanics control robustness in mammalian embryogenesis. 2023

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MISC (30)：

鳥生直哉, 中家雅隆, 山田龍, 好川貴久, 築山智之, 柳田素子, 伊佐正. NPHP1ノックアウトカニクイザルの作成による若年性ネフロン癆の病態再現. 日本内科学会雑誌. 2023. 112. 臨増. 180-180
小林憲市, 小林憲市, 築山智之, 中家雅隆, 依馬正次, 河内明宏. A MONKEY PKD1 MUTANT RECAPITULATES HUMAN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE. 日本小児泌尿器科学会雑誌. 2021. 30. 1
小林憲市, 築山智之, 影山進, 依馬正次, 河内明宏. 小児泌尿器科疾患:成育医療へのリレー基礎研究が切り開く成育医療の未来. 日本泌尿器科学会総会. 2019. 107回. SY9-7
Seita Yasunari, Tsukiyama Tomoyuki, Azami Takuya, Kobayashi Kenichi, IWATANI Chizuru, TSUCHIYA Hideaki, Nakaya Masataka, Tanabe Hideyuki, Hitoshi Seiji, Miyoshi Hiroyuki, et al. Comprehensive evaluation of ubiquitous promoters suitable for the generation of transgenic cynomolgus monkeys†. Biology of Reproduction. 2019
NAKAYA Masataka, NAKAGAWA Takahiro, FUKUDA Koji, IWAKIRI Teppei, IZUMI Hiroyuki, ITAGAKI Iori, NAKAMURA Shinichiro, KAWAUCHI Akihiro, EMA Masatsugu, TSUKIYAMA Tomoyuki, et al. Hereditary kidney disease modeling in cynomolgus monkeys using genome editing. The Journal of Reproduction and Development Supplement. 2019. 112. 0. P-103-P-103

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Patents (1)：

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Education (4)：

Professional career (1)：

Work history (7)：

2023/04 - 現在 Kyoto University Institute for the Advanced Study of Human Biology (WPI-ASHBi), Primate Genome Engineering Core (PRiME) Core Head
2019/04 - 現在 Shiga University of Medical Science Research Center for Animal Life Science
2020/01 - 2023/03 Kyoto University Institute for the Advanced Study of Human Biology (WPI-ASHBi)
2014/11 - 2019/03 Shiga University of Medical Science Research Center for Animal Life Science
2014/04 - 2014/10 Shiga University of Medical Science Research Center for Animal Life Science

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Committee career (1)：

Awards (1)：

Association Membership(s) (2)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , SOCIETY FOR REPRODUCTION AND DEVELOPMENT

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