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J-GLOBAL ID：201502218848409087
Reference number：15A1274137 第31回 注目の遺伝子 統合失調症発症脆弱性分子DISC1の研究から明らかになった課題と新機能
TSUBOI DAISUKE
About TSUBOI DAISUKE
(名古屋大 大学院医学系研究科 神経情報薬理学)
, About 名古屋大 大学院医学系研究科 神経情報薬理学
MORI DAISUKE
About MORI DAISUKE
(名古屋大 脳とこころの研究セ 研究開発部門)
, About 名古屋大 脳とこころの研究セ 研究開発部門
KURODA KEISUKE
About KURODA KEISUKE
(名古屋大 大学院医学系研究科 神経情報薬理学)
, About 名古屋大 大学院医学系研究科 神経情報薬理学
KAIBUCHI KOZO
About KAIBUCHI KOZO
(名古屋大 大学院医学系研究科 神経情報薬理学)
About 名古屋大 大学院医学系研究科 神経情報薬理学
Material：
分子精神医学
(Japanese Journal of Molecular Psychiatry)
About 分子精神医学
Volume： 15 Issue： 4 Page： 301-303 Publication year： Oct. 10, 2015
JST Material Number： L4218A ISSN： 1345-9082 Document type： Article
Article type： 解説 Country of issue： Japan (JPN) Language： JAPANESE (JA)
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*schizophrenia
,...
About schizophrenia
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*DISC1
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About DISC1
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JST classification (3)：
JST classification
Category name(code) classified by JST.
Mental disorders
Category name(code) classified by JST.
(GR03000A)
, Basic neurology
About Mental disorders
(GN01020W)
, Research methods in genetics
About Basic neurology
(EC01020N)
About Research methods in genetics
Reference (5)：
- St Clair D, Blackwood D, Muir W et al : Association within a family of a balanced autosomal translocation with major mental illness. Lancet 336 : 13-16, 1990
- Millar JK, Wilson-Annan JC, Anderson S et al : Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet 9 : 1415-1423, 2000
- Brandon NJ, Millar JK, Korth C et al : Understanding the role of DISCI in psychiatric disease and during normal development. J Neurosci 29 : 12768-12775, 2009
- Kuroda K, Yamada S, Tanaka M et al : Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Discl gene in the mouse. Hum Mol Genet 20 : 4666-4683, 2011
- Tsuboi D, Kuroda K, Tanaka M et al : Disrupted-in-schizophrenia 1 regulates transport of ITPR1 mRNA for synaptic plasticity. Nat Neurosci 18 : 698-707, 2015
Terms in the title (8)：
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注目
, About 注目
遺伝子
, About 遺伝子
統合失調症
, About 統合失調症
発症
, About 発症
脆弱性
, About 脆弱性
分子
, About 分子
DISC1
, About DISC1
研究
About 研究
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