Kojima Ryosuke

コジマリョウスケ | Kojima Ryosuke

Affiliation and department：
Job title： Associate Professor
Homepage URL (2)： https://cbmi.m.u-tokyo.ac.jp/members , https://scholar.google.com/citations?user=lP4Uu2MAAAAJ&hl=ja

Research field (6)： Chemical biology , Biomaterials , Biomedical engineering , Biochemistry , Pharmaceuticals - chemistry and drug development , Pharmaceuticals - analytical and physicochemistry

Research keywords (9)： Extracellular vesicles , Cell-cell communication , Bioluminescence Imaging , cancer , exosome , Drug Delivery System , Fluorescence imaging , Synthetic Biology , Chemical Biology

Research theme for competitive and other funds (9)：

2022 - 2028 Research on intracellular degradation focusing on membranous structures
2022 - 2025 合成生物学的手法による細胞外小胞の包括的理解と発展的利用
2019 - 2024 多次元・ネットワーク化計測による細胞外微粒子の多様性と動態の解明
2020 - 2023 機能性小分子・タンパク質ペアを利用したがん蛍光イメージングの新手法
2020 - 2023 Exploiting exosome biology to design polyvalent targeting strategies for in situ cell programming

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Papers (42)：

Barcoding of small extracellular vesicles with CRISPR-gRNA enables comprehensive, subpopulation-specific analysis of their biogenesis/release regulators. 2023
Jingwen Shou, Ayumi Komazawa, Yuusaku Wachi, Minoru Kawatani, Hiroyoshi Fujioka, Spencer John Spratt, Takaha Mizuguchi, Kenichi Oguchi, Hikaru Akaboshi, Fumiaki Obata, et al. Super-resolution vibrational imaging based on photoswitchable Raman probe. Science advances. 2023. 9. 24. eade9118
Takafumi Kasai, Kyohhei Fujita, Toru Komatsu, Tasuku Ueno, Ryosuke Kojima, Kenjiro Hanaoka, Yasuteru Urano. Development of near-infrared fluorescence probe for the selective detection of severe hypoxia. 2023
Hiroyoshi Fujioka, Minoru Kawatani, Spencer John Spratt, Ayumi Komazawa, Yoshihiro Misawa, Jingwen Shou, Takaha Mizuguchi, Hina Kosakamoto, Ryosuke Kojima, Yasuteru Urano, et al. Activatable Raman Probes Utilizing Enzyme-Induced Aggregate Formation for Selective Ex Vivo Imaging. Journal of the American Chemical Society. 2023
Daisuke Yoshida, Mako Kamiya, Shun Kawashima, Takafusa Yoshioka, Haruaki Hino, Atsuki Abe, Kyohhei Fujita, Ryosuke Kojima, Aya Shinozaki-Ushiku, Yasuteru Urano, et al. Rapid imaging of thymoma and thymic carcinoma with a fluorogenic probe targeting γ-glutamyltranspeptidase. Scientific reports. 2023. 13. 1. 3757-3757

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MISC (14)：

小嶋良輔, 國武厚貴. 合成生物学的アプローチが可能とする細胞外小胞の理解と発展的利用. 生化学. 2023. 95. 2. 194-200
小嶋良輔. “Designer EV”の開発の現状と将来展望. 実験医学増刊. 2021. 39. 20
Ryosuke Kojima (Editor). Methods in Molecular Biology, Mammalian Cell Engineering. 2021
小嶋良輔. 遺伝子工学的アプローチを利用したエクソソームのエンジニアリングとその応用. 膜. 2020. 2. 62-67
小嶋良輔. Top Researchers インタビュー. 2019

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Patents (2)：

Library of barcoded extracellular vesicles
New NIR-emitting luciferins

Education (3)：

- 2014 The University of Tokyo Graduate School of Pharmaceutical Sciences
- 2009 The University of Tokyo Department of Pharmaceutical Sciences
- 2005 Komaba-toho High School

Professional career (1)：

PhD (The University of Tokyo)

Work history (10)：

2022/11 - 現在 Nagoya University, Institute of Nano-Life-Systems, Institutes of Innovation for Future Society Institute of Innovation for Future Society Nano-Life System Visiting Associate Professor
2022/10 - 現在 The University of Tokyo Graduate School of Medicine Associate Professor
2022/04 - 現在 JST FOREST researcher
2020/04 - 2022/10 Nagoya University Institute of Innovation for Future Society Nano-Life System Visiting Assistant Professor
2017/07 - 2022/09 The University of Tokyo Graduate School of Medicine Assistant Professor

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Awards (10)：

2023/04 - MEXT Young Scientist Prize
2022/04 - CREST Fine Particles, Young Innovator Award
2019/03 - Human Frontier Science Program (HFSP) Career Development Award,
2018/09 - 12th Bio-Related Chemistry Symposium Best Lectureship Award
2018/06 - 13th Meeting of Japanese Society for Chemical Biology Royal Society of Chemistry Poster Award

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Association Membership(s) (4)：

Japanese Society of Chemical Biology , The Pharmaceutical Society of Japan , The Japanese Biochemical Society , Japanese Society for Molecular Imaging

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