Rchr
J-GLOBAL ID:201801002135761754   Update date: Jan. 04, 2021

Shogo Nakano

Shogo Nakano
Affiliation and department:
Research field  (2): Structural biochemistry ,  Applied biochemistry
Research keywords  (5): バイオインフォマティクス ,  計算化学 ,  構造生物学 ,  酵素化学 ,  タンパク質工学
Research theme for competitive and other funds  (4):
  • 2020 - 2024 離散的配列ブロックに基づく人工タンパク質配列自在設計技術の開発と応用
  • 2018 - 2020 人工アミノ酸代謝関連酵素の全配列設計を目指した新規配列データマイニング法の開発
  • 2016 - 2018 配列データベース由来人工L-アミノ酸脱水素酵素群の合理的設計とその応用
  • 2015 - 2016 高精度全電子計算に基づくレクチン-糖鎖間相互作用解析
Papers (35):
  • Kayo Yukawa-Takamatsu, Yifei Wang, Masaki Watanabe, Yuta Takamura, Michiko Fujihara, Mariko Nakamura-Nakayama, Shoya Yamada, Shota Kikuzawa, Makoto Makishima, Mayu Kawasaki, et al. Convenient Retinoid X Receptor Binding Assay Based on Fluorescence Change of the Antagonist NEt-C343. Journal of medicinal chemistry. 2020
  • Masaki Watanabe, Michiko Fujihara, Tomoharu Motoyama, Mayu Kawasaki, Shoya Yamada, Yuta Takamura, Sohei Ito, Makoto Makishima, Shogo Nakano, Hiroki Kakuta. Discovery of a “Gatekeeper” Antagonist that Blocks Entry Pathway to Retinoid X Receptors (RXRs) without Allosteric Ligand Inhibition in Permissive RXR Heterodimers. Journal of Medicinal Chemistry. 2020
  • Shogo Nakano, Kohei Kozuka, Yuki Minamino, Hiroka Karasuda, Fumihito Hasebe, Sohei Ito. Ancestral L-amino acid oxidases for deracemization and stereoinversion of amino acids. Communications Chemistry. 2020. 3. 1
  • Shoya Yamada, Yuta Takamura, Michiko Fujihara, Mayu Kawasaki, Sohei Ito, Shogo Nakano, Hiroki Kakuta. Fluorescence properties of retinoid X receptor antagonist NEt-SB. Bioorganic & medicinal chemistry letters. 2020. 127666-127666
  • Tomoharu Motoyama, Nozomi Hiramatsu, Yasuhisa Asano, Shogo Nakano, Sohei Ito. Protein Sequence Selection Method That Enables Full Consensus Design of Artificial L-Threonine 3-Dehydrogenases With Unique Enzymatic Properties. Biochemistry. 2020
more...
MISC (8):
Patents (4):
Lectures and oral presentations  (6):
  • 配列データマイニングを用いた新規L-アミノ酸酸化酵素群の取得と構造機能解析
    (生物工学会北日本支部 2020年度オンラインシンポジウム 2020)
  • In silicoでタンパク質を創る
    (細胞を創る研究会12.0 2019)
  • Reconstruction of ancestral L-amino acid oxidase to broaden substrate selectivity
    (Enzyme Engineering XXV 2019)
  • Filling a gap between computational and experimental researches through sequence-based protein design
    (The 4th International Conference on Pharma-Food (ICPF 2018) 2018)
  • Development of INTMSAlign software to design artificial proteins and assign enzymes
    (2017)
more...
Education (3):
  • 2009 - 2012 Hiroshima University Department of Mathematical and Life Sciences
  • 2007 - 2009 Hiroshima University Department of Mathematical and Life Sciences
  • 2003 - 2007 Hiroshima University Department of Chemistry
Professional career (1):
  • 博士(理学) (広島大学)
Work history (4):
  • 2020/12 - 現在 Japan Science and Technology Agency
  • 2015/04 - 現在 University of Shizuoka School of Food and Nutritional Sciences
  • 2016/04 - 2020/03 Rikkyo University College of Science
  • 2012/04 - 2015/03 ERATO浅野酵素活性分子プロジェクト 博士研究員
Awards (4):
  • 2018/07 - 第1回静岡テックグランプリ 最優秀賞
  • 2015/10 - J. Mol. Catal. B, Enzymatic, Elsevier Outstanding Reviewer Status
  • 2011/09 - 第84回日本生化学会大会 鈴木紘一メモリアル賞
  • 2009/10 - 第82回日本生化学会大会 優秀プレゼンテーション賞
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