Rchr
J-GLOBAL ID:201801014309410989   Update date: Oct. 05, 2024

Nakada Shinichiro

Nakada Shinichiro
Affiliation and department:
Other affiliations (1):
  • Kyoto University
Homepage URL  (1): http://www.bcr.med.osaka-u.ac.jp
Research field  (1): Molecular biology
Research keywords  (4): ゲノム恒常性 ,  DNA修復 ,  ゲノム編集 ,  DNA損傷応答
Research theme for competitive and other funds  (15):
  • 2022 - 2026 Muliple nicks-induced interhomolog recombination
  • 2021 - 2025 DNA1本鎖損傷により誘導される染色体構造異常発生機構の解明
  • 2019 - 2022 DNA2本鎖切断修復制御の中核となるユビキチン依存的DNA損傷応答の解明
  • 2019 - 2022 Elucidation of the mechanism underlying DNA replication stress response regulating genomic instability
  • 2018 - 2022 New development of genome editing technologies and disease models
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Papers (41):
  • Akiko Tomita, Hiroyuki Sasanuma, Tomoo Owa, Yuka Nakazawa, Mayuko Shimada, Takahiro Fukuoka, Tomoo Ogi, Shinichiro Nakada. Inducing multiple nicks promotes interhomolog homologous recombination to correct heterozygous mutations in somatic cells. Nature communications. 2023. 14. 1. 5607-5607
  • Yoko Katsuki, Masako Abe, Seon Young Park, Wenwen Wu, Hiromasa Yabe, Miharu Yabe, Haico van Attikum, Shinichiro Nakada, Tomohiko Ohta, Michael M. Seidman, et al. RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair. Cell Reports. 2021. 37. 4. 109879-109879
  • Yasuyoshi Oka, Motoharu Hamada, Yuka Nakazawa, Hideki Muramatsu, Yusuke Okuno, Koichiro Higasa, Mayuko Shimada, Honoka Takeshima, Katsuhiro Hanada, Taichi Hirano, et al. Digenic mutations in ALDH2 and ADH5 impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome. SCIENCE ADVANCES. 2020. 6. 51
  • Shojiro Inano, Koichi Sato, Yoko Katsuki, Wataru Kobayashi, Hiroki Tanaka, Kazuhiro Nakajima, Shinichiro Nakada, Hiroyuki Miyoshi, Kerstin Knies, Akifumi Takaori-Kondo, et al. RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination. Molecular cell. 2020. 78. 1. 192-192
  • Remi Akagawa, Hai Thanh Trinh, Liton Kumar Saha, Masataka Tsuda, Kouji Hirota, Shintaro Yamada, Atsushi Shibata, Masato T Kanemaki, Shinichiro Nakada, Shunichi Takeda, et al. UBC13-Mediated Ubiquitin Signaling Promotes Removal of Blocking Adducts from DNA Double-Strand Breaks. iScience. 2020. 23. 4. 101027-101027
more...
MISC (21):
Patents (3):
Education (2):
  • 2001 - 2005 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
  • 1992 - 1998 Tokyo Medical and Dental University Faculty of Medicine School of Medicine
Professional career (1):
  • 博士(医学) (東京医科歯科大学)
Awards (6):
  • 2018 - 日本放射線影響学会 学会賞
  • 2018 - 第9回 武田科学振興財団 薬科学シンポジウムPoster Award
  • 2017 - 日本医師会研究奨励賞
  • 2015 - 大阪大学総長顕彰
  • 2014 - 大阪大学総長奨励賞
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