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J-GLOBAL ID：201802267482932536   Reference number：18A0507713

Reduced expression of Na⁺/Ca²⁺ exchangers is associated with cognitive deficits seen in Alzheimer’s disease model mice

Na~+/Ca~2+交換体の発現低下はアルツハイマー病モデルマウスにみられる認知障害と関連している【Powered by NICT】

Author (15)： Moriguchi Shigeki (Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan) ,  Kita Satomi (Department of Pharmacology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Kita Satomi (Department of Pharmacology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Japan) ,  Fukaya Masahiro (Department of Anatomy, Kitasato University School of Medicine, Sagamihara, Japan) ,  Osanai Makoto (Tohoku University, Graduate School of Medicine, Sendai, Japan) ,  Inagaki Ryo (Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan) ,  Sasaki Yuzuru (Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan) ,  Izumi Hisanao (Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan) ,  Horie Kyoji (Department of Physiology II, Nara Medical University, Nara, Japan) ,  Takeda Junji (Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan) ,  Saito Takashi (Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Saitama, Japan) ,  Sakagami Hiroyuki (Department of Anatomy, Kitasato University School of Medicine, Sagamihara, Japan) ,  Saido Takaomi C. (Laboratory for Proteolytic Neuroscience, RIKEN Brain Science Institute, Saitama, Japan) ,  Iwamoto Takahiro (Department of Pharmacology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan) ,  Fukunaga Kohji (Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan)
Material： Neuropharmacology
Volume： 131  Page： 291-303  Publication year： 2018 
JST Material Number： H0537A  ISSN： 0028-3908  CODEN： NEPHBW  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Na⁺/Ca²⁺...

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Thesaurus term： calcineurin ,  mRNA ,  Eumetopias jubata ,  memory disorder ,  Calmodulin ,  gene ,  Mammalia ,  Cell Membrane ,  synapse ,  *Alzheimer Disease ,  depolarization (physiology) ,  protein kinase ,  Phenotype ,  NCX2 ,  isoform ,  Vertebrata ,  Endomembrane system

Author keywords (4)： Na⁺/Ca²⁺ exchangers ,  Long-term potentiation ,  Calcium/calmodulin-dependent protein kinase II ,  Memory deficit

JST classification (2)： Basic neurology  (GN01020W) ,  Receptors on cell membrane  (EF04030C)

Terms in the title (4)： 発現 ,  アルツハイマー病 ,  モデルマウス ,  認知障害