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J-GLOBAL ID：201802269107901786   Reference number：18A0611426

Dok-3 and Dok-1/-2 adaptors play distinctive roles in cell fusion and proliferation during osteoclastogenesis and cooperatively protect mice from osteopenia

Dok-3とDok-1/ 2アダプターは破骨細胞形成時の細胞融合と増殖における特徴的な役割を果たすと骨減少症からマウスを保護する【Powered by NICT】

Author (9)： Kajikawa Shuhei (Division of Genetics, The Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan) ,  Taguchi Yuu (Division of Cellular and Molecular Biology, The Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan) ,  Hayata Tadayoshi (Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan) ,  Ezura Yoichi (Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan) ,  Ueta Ryo (Division of Genetics, The Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan) ,  Arimura Sumimasa (Division of Genetics, The Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan) ,  Inoue Jun-ichiro (Division of Cellular and Molecular Biology, The Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan) ,  Noda Masaki (Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan) ,  Yamanashi Yuji (Division of Genetics, The Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 498  Issue： 4  Page： 967-974  Publication year： 2018 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Bone mass is determined by coo...

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Thesaurus term： Cell Count ,  osteogenesis ,  Bone Resorption ,  osteoblast ,  macrophage ,  pathophysiology ,  *osteoclast ,  Bone Marrow ,  homeostasis ,  myeloid cell ,  *Cell Fusion ,  Bone Density ,  monocyte ,  *osteoclast cell formation
Semi thesaurus term： *骨減少 , 【Automatic Indexing@JST】

Author keywords (4)： Dok ,  Osteoclastogenesis ,  Cell-to-cell fusion ,  Osteopenia

JST classification (2)： Skeletal system  (EJ10030R) ,  Function of cell components  (EF03060C)

Terms in the title (7)： アダプター ,  破骨細胞形成 ,  細胞融合 ,  増殖 ,  役割 ,  骨減少症 ,  マウス