Art

J-GLOBAL ID：201902226335947108   Reference number：19A0780753

Screening of a library of traditional Chinese medicines to identify anti-malarial compounds and extracts

抗マラリア化合物および抽出物を同定するための伝統的漢方薬ライブラリーのスクリーニング【JST・京大機械翻訳】

Author (6)： Nonaka Motohiro (National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan) ,  Murata Yuho (National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan) ,  Takano Ryo (National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan) ,  Han Yongmei (National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan) ,  Kabir Md. Hazzaz Bin (National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan) ,  Kato Kentaro (National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan)
Material： Malaria Journal (Web)
Volume： 17  Issue： 1  Page： 244  Publication year： 2018 
JST Material Number： U7332A  ISSN： 1475-2875  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Abstract/Point： Malaria is a major infectious ...

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Thesaurus term： *screening (inspection) ,  Plasmodium falciparum ,  natural material ,  antimalarial drug ,  Southeast Asia ,  life cycle ,  inhibition of multiplication ,  *Malaria ,  *Chinese drug ,  cytotoxicity ,  *educt ,  Plasmodium ,  anti-malarial activity ,  microorganism ,  protozoa ,  Sporozoa ,  nitrogen heterocyclic compound ,  aromatic chlorine compound ,  polynuclear aromatic compound ,  diamine ,  tertiary amine ,  secondary amine ,  oxygen heterocyclic compound ,  pyridinium ,  protoberberine alkaloid ,  phenol ether
Semi thesaurus term： Plasmodium ,  抗マラリア活性 , 【Automatic Indexing@JST】

Author keywords (4)： Antimalarial drugs ,  Drug screening ,  Traditional Chinese medicine ,  Plasmodium falciparum

JST classification (1)： Basic research of antiprotozoan drugs and anthelmintics  (GW17080G)

Substance index (2)： Chloroquine ,  Berberine

Reference (19)：

• World malaria report 2016; 2016; CR1; citation_publisher=World Health Organization
• Lancet; A large focus of naturally acquired Plasmodium knowlesi infections in human beings; B Singh, L Kim Sung, A Matusop, A Radhakrishnan, SSG Shamsul, J Cox-Singh; 363; 2004; 1017-1024; 10.1016/S0140-6736(04)15836-4; citation_id=CR2
• Cell; Artemisinin: discovery from the Chinese herbal garden; LH Miller, X Su; 146; 2011; 855-858; 10.1016/j.cell.2011.08.024; citation_id=CR3
• Cold Spring Harb Perspect Med; Antimalarial drug resistance: a threat to malaria elimination; D Menard, A Dondorp; 7; 2017; 025619; 10.1101/cshperspect.a025619; citation_id=CR4
• ChemMedChem; Malaria chemotherapeutics part I: history of antimalarial drug development, currently used therapeutics, and drugs in clinical development; M Schlitzer; 2; 2007; 944-986; 10.1002/cmdc.200600240; citation_id=CR5

Terms in the title (6)： マラリア ,  抽出物 ,  同定 ,  漢方薬 ,  ライブラリー ,  スクリーニング