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J-GLOBAL ID：201902237731050887   Reference number：19A0694245

Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin-fixed paraffin-embedded specimens

ホルマリン固定パラフィン包埋試料からの標的濃縮による癌の分子プロファイリングのための包括的アッセイ

Author (42)： Kohsaka Shinji (Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan) ,  Tatsuno Kenji (Genome Science Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan) ,  Ueno Toshihide (Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan) ,  Nagano Masaaki (Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan) ,  Nagano Masaaki (Department of Thoracic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Shinozaki-Ushiku Aya (Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Ushiku Tetsuo (Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Takai Daiya (Department of Clinical Laboratory, The University of Tokyo Hospital, Tokyo, Japan) ,  Ikegami Masachika (Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan) ,  Ikegami Masachika (Department of Orthopedic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Kobayashi Hiroshi (Department of Orthopedic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Kage Hidenori (Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Ando Mizuo (Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Hata Keisuke (Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Ueda Hiroki (Biological Data Science Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan) ,  Yamamoto Shogo (Genome Science Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan) ,  Kojima Shinya (Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan) ,  Oseto Kumiko (Department of Clinical Genomics, The University of Tokyo Hospital, Tokyo, Japan) ,  Akaike Keisuke (Department of Orthopedic Surgery, Juntendo University, Graduate School of Medicine, Tokyo, Japan) ,  Suehara Yoshiyuki (Department of Orthopedic Surgery, Juntendo University, Graduate School of Medicine, Tokyo, Japan) ,  Hayashi Takuo (Department of Human Pathology, Juntendo University, Graduate School of Medicine, Tokyo, Japan) ,  Saito Tsuyoshi (Department of Human Pathology, Juntendo University, Graduate School of Medicine, Tokyo, Japan) ,  Saito Tsuyoshi (Intractable Disease Research Center, Juntendo University, Graduate School of Medicine, Tokyo, Japan) ,  Takahashi Fumiyuki (Department of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan) ,  Takahashi Kazuhisa (Department of Respiratory Medicine, Juntendo University, Graduate School of Medicine, Tokyo, Japan) ,  Takamochi Kazuya (Department of General Thoracic Surgery, Juntendo University, Graduate School of Medicine, Tokyo, Japan) ,  Suzuki Kenji (Department of General Thoracic Surgery, Juntendo University, Graduate School of Medicine, Tokyo, Japan) ,  Nagayama Satoshi (Gastroenterological Center, Department of Gastroenterological Surgery, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan) ,  Oda Yoshinao (Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan) ,  Mimori Koshi (Department of Surgery, Kyushu University Beppu Hospital, Beppu, Japan) ,  Ishihara Soichiro (Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Yatomi Yutaka (Department of Clinical Laboratory, The University of Tokyo Hospital, Tokyo, Japan) ,  Nagase Takahide (Department of Respiratory Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Nakajima Jun (Department of Thoracic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Tanaka Sakae (Department of Orthopedic Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Fukayama Masashi (Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Oda Katsutoshi (Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Nangaku Masaomi (Department of Clinical Genomics, The University of Tokyo Hospital, Tokyo, Japan) ,  Miyazono Kohei (Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan) ,  Miyagawa Kiyoshi (Laboratory of Molecular Radiology, Center for Disease Biology and Integrative Medicine, The University of Tokyo, Tokyo, Japan) ,  Aburatani Hiroyuki (Genome Science Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan) ,  Mano Hiroyuki (Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan)
Material： Cancer Science (Web)  (Cancer Sci (Web))
Volume： 110  Issue： 4  Page： 1464-1479  Publication year： 2019 
JST Material Number： U0505A  ISSN： 1349-7006  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *gene ,...
Semi thesaurus term： Whole Exome Sequencing

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Author keywords (5)： clinical sequencing ,  junction capture method ,  molecular profiling ,  personalized medicine ,  Todai OncoPanel

JST classification (2)： Basic oncology in general  (GE02010R) ,  Tumors(=neoplasms)of respiratory system  (GI04000G)

Terms in the title (7)： ホルマリン固定パラフィン包埋 ,  試料 ,  標的 ,  濃縮 ,  癌 ,  分子プロファイリング ,  アッセイ