Art

J-GLOBAL ID：201902275889258397   Reference number：19A1712617

L-carnitine prevents ammonia-induced cytotoxicity and disturbances in intracellular amino acid levels in human astrocytes

L-カルニチンはヒト星状細胞の細胞内アミノ酸レベルにおけるアンモニア誘導細胞毒性と外乱を防ぐ【JST・京大機械翻訳】

Author (7)： Wang Ting (Division of Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan) ,  Suzuki Kazuyuki (Division of Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan) ,  Suzuki Kazuyuki (Department of Nutritional Science, Morioka University, Takizawa, Japan) ,  Kakisaka Keisuke (Division of Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan) ,  Onodera Mio (Division of Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan) ,  Sawara Kei (Division of Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan) ,  Takikawa Yasuhiro (Division of Hepatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan)
Material： Journal of Gastroenterology and Hepatology
Volume： 34  Issue： 7  Page： 1249-1255  Publication year： 2019 
JST Material Number： W2642A  ISSN： 0815-9319  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： BACKGROUND AND AIM: L-carnitin...

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Thesaurus term： side chain ,  metabolite ,  *human ,  administration (biology) ,  *Ammonia ,  coprocessing ,  active oxygen ,  *cytotoxicity ,  *astrocyte ,  therapy ,  lactate dehydrogenase ,  Metabolomics ,  aliphatic amine ,  aliphatic alcohol ,  aliphatic carboxylic acid ,  aminoalcohol ,  aminocarboxylic acid ,  tertiary amine ,  secondary alcohol ,  hydroxy acid ,  branched-chain amino acid ,  primary amine ,  amino acid ,  carboxamide ,  dicarboxylic acid

Author keywords (5)： branched-chain amino acids ,  carnitine ,  human astrocyte ,  hyperammonemia ,  oxidative stress

JST classification (4)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  (GE02030N) ,  Gene expression  (EC02040Q) ,  Basic medicine on digestive system  (GH01020E)

Substance index (3)： Carnitine ,  Isoleucine ,  Glutamine

Terms in the title (8)： L-カルニチン ,  ヒト ,  星状細胞 ,  アミノ酸 ,  アンモニア ,  誘導 ,  細胞毒性 ,  外乱