Art

J-GLOBAL ID：201902291414325318   Reference number：19A0364275

Microsomal prostaglandin E synthase-1 is a critical factor in dopaminergic neurodegeneration in Parkinson’s disease

ミクロソームプロスタグランジンEシンターゼ-1はParkinson病におけるドーパミン作動性神経変性の重要な因子である【JST・京大機械翻訳】

Author (11)： Ikeda-Matsuo Yuri (Laboratory of Pharmacology, Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Hokuriku University, Japan) ,  Ikeda-Matsuo Yuri (Laboratory of Pharmacology, School of Pharmaceutical Sciences, Kitasato University, Japan) ,  Miyata Hajime (Department of Neuropathology, Research Institute for Brain and Blood Vessels - AKITA, Japan) ,  Mizoguchi Tomoko (Laboratory of Pharmacology, School of Pharmaceutical Sciences, Kitasato University, Japan) ,  Ohama Eisaku (Kurashiki Heisei Hospital, Japan) ,  Naito Yasuhito (Laboratory of Pharmacology, School of Pharmaceutical Sciences, Kitasato University, Japan) ,  Uematsu Satoshi (Department of Mucosal Immunology, School of Medicine, Chiba University, Japan) ,  Uematsu Satoshi (Division of Innate Immune Regulation, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Japan) ,  Akira Shizuo (Laboratory of Host Defense, WPI Immunology Frontier Research Center, Osaka University, Japan) ,  Sasaki Yasuharu (Laboratory of Pharmacology, School of Pharmaceutical Sciences, Kitasato University, Japan) ,  Tanabe Mitsuo (Laboratory of Pharmacology, School of Pharmaceutical Sciences, Kitasato University, Japan)
Material： Neurobiology of Disease  (Neurobiol Dis)
Volume： 124  Page： 81-92  Publication year： 2019 
JST Material Number： W1774A  ISSN： 0969-9961  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Parkinson’s disease (PD) is a ...

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Thesaurus term： *Parkinson's disease ,  enzyme ,  Corpus Striatum ,  neurotoxicity ,  *microsome ,  Mus musculus ,  neuron ,  in vitro experiment ,  Substantia Nigra ,  Up-Regulation ,  pathogenesis ,  mPGES-1 ,  Dopaminergic Neurons ,  Myomorpha ,  Mesencephalon ,  telencephalon ,  Prosencephalon ,  basal ganglia ,  catecholamine ,  primary amine
Semi thesaurus term： *神経変性 , 【Automatic Indexing@JST】

Author keywords (9)： Parkinson’s disease ,  Neurodegeneration ,  Prostaglandin E₂ ,  Microsomal prostaglandin E synthase ,  Neuroinflammation ,  Dopamine ,  Neurotoxicity ,  Lewy bodies ,  6-hydroxydopamine

JST classification (1)： Basic neurology  (GN01020W)

Substance index (1)： Dopamine

Terms in the title (6)： ミクロソーム ,  プロスタグランジンEシンターゼ ,  Parkinson病 ,  ドーパミン ,  神経変性 ,  因子