笹井美和

ササイミワ | Sasai Miwa

所属機関・部署：
職名：准教授
ホームページURL (1件)： http://kaken.nii.ac.jp/d/r/30631551.ja.html

研究分野 (1件)：免疫学

研究キーワード (2件)：寄生虫学 , 自然免疫

競争的資金等の研究課題 (4件)：

論文 (68件)：

Yuta Tachibana, Miwa Sasai, Masahiro Yamamoto. CRISPR screens identify genes essential for in vivo virulence among proteins of hyperLOPIT-unassigned subcellular localization in Toxoplasma. mBio. 2024. 15. 9. e0172824
Masaaki Okamoto, Ayumi Kuratani, Daisuke Okuzaki, Naganori Kamiyama, Takashi Kobayashi, Miwa Sasai, Masahiro Yamamoto. Tff1-expressing Tregs in lung prevent exacerbation of Bleomycin-induced pulmonary fibrosis. Frontiers in immunology. 2024. 15. 1440918-1440918
Tokuju Okano, Hiroshi Ashida, Noriko Komatsu, Masayuki Tsukasaki, Tamako Iida, Marie Iwasawa, Yuto Takahashi, Yasuo Takeuchi, Takanori Iwata, Miwa Sasai, et al. Caspase-11 mediated inflammasome activation in macrophages by systemic infection of A. actinomycetemcomitans exacerbates arthritis. International journal of oral science. 2024. 16. 1. 54-54
Chisato Sakuma, Sayaka Shizukuishi, Michinaga Ogawa, Yuko Honjo, Haruko Takeyama, Jun-Lin Guan, Jeffery Weiser, Miwa Sasai, Masahiro Yamamoto, Makoto Ohnishi, et al. Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition. Cell reports. 2024. 43. 5. 114131-114131
Fumiaki Ihara, Hisako Kyan, Yasuhiro Takashima, Fumiko Ono, Kei Hayashi, Tomohide Matsuo, Makoto Igarashi, Yoshifumi Nishikawa, Kenji Hikosaka, Hirokazu Sakamoto, et al. Far-East Asian Toxoplasma isolates share ancestry with North and South/Central American recombinant lineages. Nature communications. 2024. 15. 1. 4278-4278

MISC (3件)：

Miwa Sasai, Masahiro Yamamoto. Gate-16 is required for LC3-independent antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases. CYTOKINE. 2017. 100. 29-29
Payal Mehta, Jill Henault, Jennifer Martinez, Jeffery Riggs, Jane Tian, Lorraine Clarke, Miwa Sasai, Eicke Latz, Melanie Brinkmann, Akiko Lwasaki, et al. LC3-associated phagocytosis mediates IFN-alpha secretion in response to DNA-immune complexes. JOURNAL OF IMMUNOLOGY. 2014. 192
Michal Tal, Miwa Sasai, Akiko Iwasaki. RLR signaling is amplified by reactive oxygen species and dysfunctions in autophagy. JOURNAL OF IMMUNOLOGY. 2011. 186

書籍 (2件)：

講演・口頭発表等 (30件)：

Uncovering a novel role of PLCb in selectively mediating TCR signaling in CD8+ but not CD4+ T cells
(第43回分子生物学会・ワークショップ (口頭) 2020)
PLCβ plays an important role in CD8 T cell-mediated host defense against Toxoplasma gondii
(第46回日本免疫学会学術集会 2017)
Role of GABARAP subfamily in the regulation of non-canonical inflammasome activation
(第46回日本免疫学会学術集会 2017)
Critical roles of GABARAPs on interferon-mediated cell-autonomous immune responses against T. gondii infection
(第46回日本免疫学会学術集会 2017)
Gate-16 is required for LC3-independent antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases
(CYTOKINE2017 2017)

経歴 (5件)：

受賞 (5件)：

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笹井 美和