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J-GLOBAL ID：200901026175275492 Update date: Mar. 17, 2025

Igawa Kazunobu

イガワカズノブ | Igawa Kazunobu

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Affiliation and department：
Homepage URL (1)： https://www.kumadai-igawa.info/

Research field (2)： Synthetic organic chemistry , Structural/physical organic chemistry

Research theme for competitive and other funds (21)：

2023 - 2026 Development of Silicon Containing Biomolecule based on Stereocontrol of Asymmetric Silicon
2020 - 2025 Development of DYASIN: Novel Approach to Enantioenriched Chiral Molecules
2020 - 2023 GSK-3活性化作用に基づいた心臓線維化抑制薬開発に向けた基盤研究
2020 - 2023 キラルケイ素分子の精密合成法開発と新規生物活性分子創製への展開
2021 - 2022 Design of Bifunctional Selenium Catalysts and Its Application to Precise Organic Synthesis

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Papers (90)：

Masaki Arioka, Wang Yi, Kazunobu Igawa, Shin Ishikane, Fumi Takahashi-Yanaga. Differentiation-inducing factor-1 inhibits EMT by proteasomal degradation of TAZ and YAP in cervical and colon cancer cell lines. European journal of pharmacology. 2024. 177184-177184
Riki Iwai, Hiroyuki Yoshida, Yuki Arakawa, Shunsuke Sasaki, Yuuto Iida, Kazunobu Igawa, Tsuneaki Sakurai, Satoshi Suzuki, Masatoshi Tokita, Junji Watanabe, et al. Near-room-temperature π-conjugated nematic liquid crystals in molecules with a flexible seven-membered ring structure. Aggregate. 2024. 6. e660
Masaki Arioka, Koichi Miura, Ruzhe Han, Kazunobu Igawa, Fumi Takahashi-Yanaga, Toshiyuki Sasaguri. Mammalian target of differentiation-inducing factor-1 is mitochondrial malate dehydrogenase for activation of AMP-activated protein kinase and induction of mitochondrial fission. Life Sciences. 2024. 351. 122807-122807
Akihiro Kuroo, Kazunobu Igawa, Katsuhiko Tomooka. Stereoselective synthesis of multi-functionalized chiral silacyclopentanes. Chemistry Letters. 2024
Takehiro Kishigami, Shin Ishikane, Masaki Arioka, Kazunobu Igawa, Yosuke Nishimura, Fumi Takahashi-Yanaga. 2,5-Dimethyl-celecoxib induces early termination of inflammatory responses by transient macrophage accumulation and inhibits the progression of cardiac remodeling in a mouse model of cryoinjury-induced myocardial infarction. Journal of Pharmacological Sciences. 2024. 154. 2. 97-107

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MISC (54)：

臼井一晃, 成田望実, 江藤亮介, 飯塚直子, 梅野智大, 井川和宣, 友岡克彦, 今井喜胤, 唐澤悟. Oxidation of phosphine in the inner rim of helicene and chiroptical properties. 基礎有機化学討論会要旨集. 2022. 32nd (CD-ROM)
Kazunobu Igawa, Kazuhiro Uehara, Yuuya Kawasaki, Katsuhiko Tomooka. Stereochemical study on planar-chiral cyclic molecules using polysaccharide-based column chromatography. Chirality. 2022
吉田優, 目黒友啓, 寺嶌紀和, 伊藤晴海, 小池悠華, 井川和宣, 友岡克彦, 喜井勲, 細谷孝充. アジド化合物とホスフィン類との反応を活用した新しい分子連結法の開発. 有機合成シンポジウム講演予稿集. 2019. 115th
Kazunobu Igawa, Yuuya Kawasaki, Yusuke Ano, Takeru Kashiwagi, Kouhei Ogawa, Jun Ichi Hayashi, Ryota Morita, Yukari Yoshioka, Kazuhiro Uehara, Katsuhiko Tomooka. Preparation of enantioenriched chiral organic molecules by dynamic asymmetric induction from a outer chiral source. Chemistry Letters. 2019. 48. 7. 726-729
山田泰之, 三原のぞみ, 森田健太郎, 高谷光, 北河康隆, 井川和宣, 友岡克彦, 田中健太郎. 超分子会合体形成反応を利用した窒素架橋鉄ポルフィリノイド二核錯体型エタン酸化触媒の活性化. ホスト-ゲスト・超分子化学シンポジウム講演要旨集. 2018. 16th

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Patents (8)：

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Lectures and oral presentations (67)：

軸不斉を有するブロモビフェニル誘導体の合成および動的立体化学挙動の解析
(日本化学会第105春季年会 2025)
面不斉グリシンを含むオリゴグリシンの合成とその立体化学解析
(日本化学会第105春季年会 2025)
DYASIN法を基盤とするキラルアミノ酸合成法の開発(II)
(日本化学会第105春季年会 2025)
DYASIN法を基盤とするキラルアミノ酸合成法の開発 (I)
(日本化学会第105春季年会 2025)
動的軸不斉を有するピリジン-ナフトール系分子の設計,合成および立体化学挙動の解析
(日本化学会第105春季年会 2025)

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Education (2)：

- 2003 Tokyo Institute of Technology Science of Engineering
- 2003 Tokyo Institute of Technology Graduate School, Division of Science and Engineering Applied Chemistry

Professional career (1)：

Doctor of Engineering (Tokyo Institute of Technology)

Work history (6)：

2022/09 - 現在 Kumamoto University
2007/04 - 2022/08 Kyushu University Institute for Materials Chemistry and Engineering
2004/12 - 2007/03 - 東京工業大学大学院理工学研究科助手
2003 - 2004 万有製薬株式会社合成技術研究所研究員
2003 - 2004 Banyu Pharmaceutical Co., LTD. Process R & D Researcher

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Awards (10)：

2023/12 - The 16th International Conference on Cutting-Edge Organic Chemistry in Asia Asian Core Program Lectureship Award (Taiwan) Chemistry of Chiral Silicon Molecules: Approaches to Chiral Silacarboxylic Acids and Their Ester Derivatives
2016 - 宇部興産学術振興財団宇部興産学術振興財団第57回学術奨励賞
2014 - ケイ素化学協会ケイ素化学協会奨励賞
2014 - 万有生命科学振興国際交流財団 Banyu Chemist Award (2014)
2012 - 日本化学会若い世代の特別講演賞

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Association Membership(s) (6)：

ケイ素化学協会 , 有機合成化学協会 , 日本化学会 , The Society of Silicon Chemistry Japan , The Society of Synthetic Organic Chemistry, Japan , The Chemical Society of Japan

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