Research field (2):
Synthetic organic chemistry
, Structural/physical organic chemistry
Research theme for competitive and other funds (21):
2023 - 2026 Development of Silicon Containing Biomolecule based on Stereocontrol of Asymmetric Silicon
2020 - 2025 Development of DYASIN: Novel Approach to Enantioenriched Chiral Molecules
2020 - 2023 GSK-3活性化作用に基づいた心臓線維化抑制薬開発に向けた基盤研究
2020 - 2023 キラルケイ素分子の精密合成法開発と新規生物活性分子創製への展開
2021 - 2022 Design of Bifunctional Selenium Catalysts and Its Application to Precise Organic Synthesis
2017 - 2020 キラルケイ素テクノロジーの開拓
2016 - 2019 Development of innovative molecular devices based on molecular inclusion reaction
2016 - 2019 Design and Synthesis of Dynamic Planar Chiral Medium-sized Cyclic Molecule
2016 - 2018 Stereochemical Study on Chiral Silicon Radical and Its Application for Novel Asymmetric Synthesis
2015 - 2017 Synthsis of Silacarboxylic Acid Derivatives and Applications Thereof
2013 - 2016 Examination of the in vivo effect of DIF, an inhibitor of G1 phase transition derived from Dictyostelium, as a new anti-cancer drug
2012 - 2016 Asymmetric Synthesis of Highly Functionalized Chiral Silicon Molecules and Application Thereof
2010 - 2012 Synthesis and Application of Planar Chiral Heterocycles
2010 - 2011 Asymmetric Synthesis of Chiral Organosilicon Compounds and Their Applications
2007 - 2008 Synthesis of Enantio-enriched Organosilane and Its Application
2006 - 2008 Development of Enantioselective Hydroalumination and Its Application to Asymmetric Synthesis of Chiral tert-Alcohol
2004 - 2007 カルポアニン転位を基盤とする不斉分子構築法の開発
2005 - 2006 キラル有機ケイ素化合物の不斉合成とその活用
2000 - 2002 新規カルボアニオン転位を基盤とする生理活性天然物合成法の開発
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Papers (87):
Masaki Arioka, Koichi Miura, Ruzhe Han, Kazunobu Igawa, Fumi Takahashi-Yanaga, Toshiyuki Sasaguri. Mammalian target of differentiation-inducing factor-1 is mitochondrial malate dehydrogenase for activation of AMP-activated protein kinase and induction of mitochondrial fission. Life Sciences. 2024. 351. 122807-122807
Takehiro Kishigami, Shin Ishikane, Masaki Arioka, Kazunobu Igawa, Yosuke Nishimura, Fumi Takahashi-Yanaga. 2,5-Dimethyl-celecoxib induces early termination of inflammatory responses by transient macrophage accumulation and inhibits the progression of cardiac remodeling in a mouse model of cryoinjury-induced myocardial infarction. Journal of Pharmacological Sciences. 2024. 154. 2. 97-107
Takahiro Moriyama, Makoto Yoritate, Naoki Kato, Azusa Saika, Wakana Kusuhara, Shunsuke Ono, Takahiro Nagatake, Hiroyuki Koshino, Noriaki Kiya, Natsuho Moritsuka, et al. Linkage-Editing Pseudo-Glycans: A Reductive α-Fluorovinyl-C-Glycosylation Strategy to Create Glycan Analogs with Altered Biological Activities. Journal of the American Chemical Society. 2024. 146. 3. 2237-2247
Yuki Arakawa, Takuma Shiba, Kazunobu Igawa. Selenium-linked cyanobiphenyl-based liquid crystal dimers: the effects of chalcogen linkage and spacer length on the twist-bend nematic phase. Liquid Crystals. 2024
臼井一晃, 成田望実, 江藤亮介, 飯塚直子, 梅野智大, 井川和宣, 友岡克彦, 今井喜胤, 唐澤悟. Oxidation of phosphine in the inner rim of helicene and chiroptical properties. 基礎有機化学討論会要旨集. 2022. 32nd (CD-ROM)
Kazunobu Igawa, Kazuhiro Uehara, Yuuya Kawasaki, Katsuhiko Tomooka. Stereochemical study on planar-chiral cyclic molecules using polysaccharide-based column chromatography. Chirality. 2022
- 2003 Tokyo Institute of Technology Science of Engineering
- 2003 Tokyo Institute of Technology Graduate School, Division of Science and Engineering Applied Chemistry
Professional career (1):
Doctor of Engineering (Tokyo Institute of Technology)
Work history (6):
2022/09 - 現在 Kumamoto University
2007/04 - 2022/08 Kyushu University Institute for Materials Chemistry and Engineering
2004/12 - 2007/03 - 東京工業大学 大学院理工学研究科 助手
2003 - 2004 万有製薬株式会社 合成技術研究所 研究員
2003 - 2004 Banyu Pharmaceutical Co., LTD. Process R & D Researcher
2004 - - Tokyo Institute of Technology Graduate School of Science and Engineering Assistant Professor
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Awards (10):
2023/12 - The 16th International Conference on Cutting-Edge Organic Chemistry in Asia Asian Core Program Lectureship Award (Taiwan) Chemistry of Chiral Silicon Molecules: Approaches to Chiral Silacarboxylic Acids and Their Ester Derivatives
2016 - 宇部興産学術振興財団 宇部興産学術振興財団 第57回学術奨励賞
2014 - ケイ素化学協会 ケイ素化学協会奨励賞
2014 - 万有生命科学振興国際交流財団 Banyu Chemist Award (2014)
2012 - 日本化学会 若い世代の特別講演賞
2012 - 有機合成化学協会 有機合成化学奨励賞
2010 - 有機合成化学協会九州山口支部 優秀論文賞
2009 - Thieme Chemistry Thieme Chemistry Journal Award 2009
2008 - 天然有機化合物討論会 第50天然有機化合物討論会奨励賞
2005 - 有機合成化学協会研究企画賞
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Association Membership(s) (6):
ケイ素化学協会
, 有機合成化学協会
, 日本化学会
, The Society of Silicon Chemistry Japan
, The Society of Synthetic Organic Chemistry, Japan
, The Chemical Society of Japan