Nakada Masahisa

ナカダマサヒサ | Nakada Masahisa

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.chem.waseda.ac.jp/home/chem.html

Research field (4)： Synthetic organic chemistry , Pharmaceuticals - chemistry and drug development , Bioorganic chemistry , Structural/physical organic chemistry

Research keywords (1)： Chemical Pharmacology,Molecular Pharmacology

Research theme for competitive and other funds (25)：

2019 - 2022 縮環部全炭素四級不斉中心の構築と異種生物活性多環式化合物の不斉全合成に関する研究
2015 - 2020 反応集積化が導く中分子戦略:高次生物機能分子の創製
2015 - 2020 Efficient Synthesis of Important Bioactive Medium-Size Polycyclic Natural Products
2015 - 2019 有用な生物機能多環式中分子の高効率合成
2014 - 2016 Research on Asymmetric Catalysis Based on Design and Synthesis of New Chiral Pincer-Type NHC Ligand

2013 - 2016 Catalytic Asymmetric Reactions of Alkenes Activated by Two Electron-Withdrawing Groups and Their Applications to Efficient Enantioselective Total Syntheses

2014 - 2015 新規不斉ピンサー型NHC配位子の設計・合成による不斉触媒反応の創出研究

2014 - 2015 Research on Asymmetric Catalysis Based on Design and Synthesis of New Chiral Pincer-Type NHC Ligand

2013 - 2015 2つの電子求引基で活性化されたアルケンの不斉触媒反応と効率的不斉全合成への活用

2013 - 2015 Catalytic Asymmetric Reactions of Alkenes Activated by Two Electron-Withdrawing Groups and Their Applications to Efficient Enantioselective Total Syntheses

2009 - 2014 Organic Synthesis Based on Reaction Integration. Development of New Methods and Creation of New Substances

2009 - 2014 Synthetic Studies on Bioactive Natural Products utilizing Integrated

2011 - 2013 Research on the design and synthesis of chiral NHC pincer ligands and their utility for asymmetric catalysis

2008 - 2010 Preparation of new chiral building blocks and their practical use in the enantioselective total synthesis of bioactive polycyclic natural products

2005 - 2007 Studies on the total synthesis and SAR of natural products that bind to tublin

2000 - 2001 Synthetic Study on Taxol via a New Route Inspired by Its Biogenesis

1998 - 2001 Total Synthesis of Natural Products Possessing Multiple Bioactivities and Isolation of Their Activities

1996 - 2000 生理活性素材開発

1994 - 1995 Catalytic Asymmetric Synthesis of Bioactive Molecules with a Benzylic Quarternary Carbon

抗腫瘍性マクロリド、リゾキシンの構造活性相関及び生物有機化学的研究

プロティンナーゼC活性化調節機構の分子レベルで解明に関する研究

PI3キナーゼ阻害剤ワ-トマンニンの合成と生物有機化学的展開

生合成類似ルートによる抗腫瘍性テルペノイド,タキソールの合成研究

生物活性多環式天然物の効率的全合成研究

生体分子の一分子検出・機能解析システムの開発と応用

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Papers (291)：

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Patents (1)：

配位子及び不斉触媒

Lectures and oral presentations (30)：

タキソールの不斉全合成研究
(第93回有機合成シンポジウム 2008)
MK8383の不斉全合成
(第55回有機合成化学協会関東シンポジウム 2008)
Studies on Enantioselective Total Syntehsis of (+)-Ophiobolin A
(2008)
Taxolの収束的不斉全合成研究
(日本薬学会第128年会 2008)
(+)-Ophiobolin Aの不斉全合成研究
(日本化学会第88春季年会 2008)

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Education (2)：

- 1984 University of Tokyo Graduate School, Division of Pharmaceutical Sciences
- 1982 University of Tokyo Faculty of Pharmaceutical Science

Professional career (3)：

博士(薬学)
Ph.D.
博士(薬学) (東京大学)

Awards (2)：

2008 - 有機合成化学協会 2008 年度(第1回)有機合成化学協会アステラス製薬・生命有機化学賞
1997 - 日本薬学会奨励賞

Association Membership(s) (7)：

国際複素環化学会 , アメリカ化学会 , International Heterocyclic Chemistry , American Chemical Society , 有機合成化学協会 , 日本薬学会 , 日本化学会

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