Rchr
J-GLOBAL ID:200901074911542236
Update date: Sep. 28, 2024
Muramatsu Shin-ichi
ムラマツ シンイチ | Muramatsu Shin-ichi
Affiliation and department:
Job title:
Visiting Professor
Research field (2):
Neuroscience - general
, Neurology
Research keywords (14):
包括脳ネットワーク
, 脳プロ
, Gene therapy
, Adeno-associated virus
, ES細胞
, レビー小体
, アルツハイマー病
, 大脳基底核
, PET
, カニクイサル
, アデノ随伴ウイルス
, ドパミン
, パーキンソン病
, 遺伝子治療
Research theme for competitive and other funds (17):
- 2022 - 2025 多機能化一本鎖抗体によるアミロイドβ凝集体細胞内スワイプ療法の開発
- 2020 - 2023 異常凝集体に対する体外診断法開発によるアルツハイマー病の早期診断と病態解明
- 2016 - 2018 Development of next-generation gene therapy and intracellular immunotherapy for Alzheimer's disease
- 2015 - 2018 Protective effects of Shati/Nat8l on the dysfunction induced by addictive drugs
- 2015 - 2017 A new mice model of bipolar disease for the drug developments
- 2014 - 2017 Gene therapy for neurodegenerative diseases using modified AAV vectors.
- 2013 - 2016 Gene therapy for epilepsy by intravascular administration of Adeno-associated virus
- 2013 - 2015 AAVベクターを応用した神経変性疾患の病態解析
- 2011 - 2013 血管内投与型AAVベクターによる神経変性疾患の病態解析
- 2011 - 2013 Gene therapy for neurodegenerative diseases using adeno-associated viral vectors that can cross the blood-brain barriers.
- 2009 - 2012 神経・精神疾患に関与する新規分子の機能解明および臨床応用への可能性
- 2007 - 2008 Studies on pathophysiology of neurodegenerative diseases using novel recombinant adeno -associated viral vectors.
- 2005 - 2006 Studies on striatal function using adeno-associated viral vectors
- 2003 - 2004 Assessment of specific cognitive function of the striatum in a primate model of Parkinson's disease.
- 2001 - 2003 Regulation of endothelial cell function by transgene expression and development of gene therapy for vascular diseases
- 2000 - 2001 Regulation of endothelial cell functions by gene transfer using viral vectors
- 1998 - 1999 GENERATION OF RECOMBINANT ADENO-ASSOCIATED VIRUS TYPE 3 BASED VECTORS
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Papers (364):
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Naotaka Izuo, Daiki Ikejima, Kyosuke Uno, Takashi Asano, Shin-Ichi Muramatsu, Atsumi Nitta. Hippocampus-specific knockdown of Shati/Nat8l impairs cognitive function and electrophysiological response in mice. Biochemical and biophysical research communications. 2024. 736. 150435-150435
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Kareem Abdou, Masanori Nomoto, Mohamed H. Aly, Ahmed Z. Ibrahim, Kiriko Choko, Reiko Okubo-Suzuki, Shin-ichi Muramatsu, Kaoru Inokuchi. Prefrontal coding of learned and inferred knowledge during REM and NREM sleep. Nature Communications. 2024
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Shin-Ichi Muramatsu. AAV vectors advance cardiac gene therapy while overcoming challenges. International journal of cardiology. 2024. 400. 131704-131704
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Yoshiaki Tanaka, Rina Takagi, Shingen Mitou, Machiko Shimmura, Tetsuya Hasegawa, Jota Amarume, Masami Shinohara, Yasushi Kageyama, Tomohiko Sasase, Takeshi Ohta, et al. Protective Effect of Pemafibrate Treatment against Diabetic Retinopathy in Spontaneously Diabetic Torii Fatty Rats. Biological & pharmaceutical bulletin. 2024
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Hajime Miyanishi, Shiori Suga, Kazuyuki Sumi, Miho Takakuwa, Naotaka Izuo, Takashi Asano, Shin-Ichi Muramatsu, Atsumi Nitta. The Role of GABA in the Dorsal Striatum-Raphe Nucleus Circuit Regulating Stress Vulnerability in Male Mice with High Levels of Shati/Nat8l. eNeuro. 2023. 10. 10
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MISC (214):
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甲州亮太, 野田昌生, 野田昌生, 島田茉莉, 伊藤真人, 村松慎一. AAVベクターによる内耳への遺伝子導入. 日本耳科学会総会・学術講演会(Web). 2023. 33rd
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野田昌生, 野田昌生, 甲州亮太, 島田Dias茉莉, 滝野直美, 伊藤美加, 伊藤真人, 村松慎一. AAVベクターによる内耳への遺伝子導入. 日本耳鼻咽喉科頭頚部外科学会会報. 2023. 126. 4
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前田絢子, 吉野鉄大, 片山琴絵, 堀場裕子, 引網宏彰, 嶋田豊, 並木隆雄, 田原英一, 南澤潔, 村松慎一, et al. Prediction Model for Deficiency-Excess Patterns, Including Medium Pattern. 日本東洋医学雑誌. 2020. 71. 4
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南 絢子, 吉野 鉄大, 片山 琴絵, 堀場 裕子, 引網 宏彰, 嶋田 豊, 並木 隆雄, 田原 英一, 南澤 潔, 村松 慎一, et al. 複数施設データを用いた医師の虚実診断の予測. 日本東洋医学雑誌. 2019. 70. 別冊. 212-212
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橋本翔子, 松葉由紀夫, 釜野直子, 三平尚美, 高野二郎, 佐原成彦, 村松慎一, 斉藤貴志, 西道隆臣. アルツハイマー病の進行に関わる新規タンパク質CAPONの機能解析. Dementia Japan. 2019. 33. 4
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Patents (5):
Professional career (1):
Work history (6):
Committee career (2):
- - 現在 日本遺伝子細胞治療学会 理事
- - 2019/05 日本東洋医学会 理事
Awards (4):
- 2019/03 - ヘルシー・ソサエティー賞
- 2011/07 - Japan Society of Gene Therapy Takara Bio Award
- 2009/06 - American Society of Gene Therapy Top Abstract
- 2000/06 - Japan Society of Gene Therapy The 6th JSGT Award
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