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Co-authoring Researcher

Fujioka Hiromichi
Osaka University Graduate School of Pharmaceutical Sciences, Molecular Pharmaceutical Sciences
Sajiki Hironao
Gifu Pharmaceutical University Faculty of Pharmaceutical Science, Faculty of Pharmaceutial Science, Gifu Pharmaceutical University Faculty of Pharmaceutical Science Department of public Health Pharmacy Laboratory of Medicinal Chemistry
医薬品化学, グリーンケミストリー, 環境化学, 有機化学, プロセス化学, 触媒有機化学, 有機合成化学, Synthetic Chemistry, Medicinal Chemistry, Organic Chemistry

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J-GLOBAL ID：201901000371334616 Update date: Feb. 26, 2025

Yoshinari Sawama

サワマヨシナリ | Yoshinari Sawama

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Affiliation and department：
Job title： Associate Professor

Research field (3)： Green/sustainable/environmental chemistry , Synthetic organic chemistry , Pharmaceuticals - chemistry and drug development

Research keywords (5)：重水素 , 天然物合成 , メカノケミカル , 不均一系触媒 , ルイス酸

Research theme for competitive and other funds (23)：

2020 - 2024 Development of efficient continuous flow synthesis method using microwave energy accumulation effect
2020 - 2023 Deuterium Science
2021 - 2023 多点反応型不安定中間体の位置選択的官能基化によるビアリール合成と応用
2020 - 2023 Multi-synthesis of deuterium-labelled biological compounds and the evaluation
2020 - 2021 炭類を原料にした人工天然ガス合成法の開発

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Papers (156)：

Shogo Moriyama, Yuto Emi, Toshifumi Nosaki, Yuki Morikawa, Takashi Shigeta, Akira Takagi, Masahiro Egi, Takashi Ikawa, Yoshinari Sawama, Shuji Akai. Total synthesis of aloin via regioselective Diels-Alder reactions connecting two 3-silylbenzynes and 2-stannylfuran. Synlett. 2025
Riku Ogasahara, Miyu Mae, Keisuke Matsuura, Sota Yoshimura, Takayoshi Ishimoto, Taro Udagawa, Kazuo Harada, Hiroyoshi Fujioka, Mako Kamiya, Rio Asada, et al. Photocatalytic Multiple Deuteration of Polyethylene Glycol Derivatives Using Deuterium Oxide. Chemistry - A European Journal. 2025
Riku Ogasahara, Miyu Mae, Yuki Itabashi, Kei Ohkubo, Keisuke Matsuura, Hyoga Shimizu, Kazuho Ban, Taro Udagawa, Hiroyoshi Fujioka, Mako Kamiya, et al. Photocatalytic and highly regioselective H/D exchange at alpha-thio C(sp3)-H bonds. 2024
Riku Ogasahara, Kazuho Ban, Miyu Mae, Shuji Akai, Yoshinari Sawama. Deuterated Alkyl Sulfonium Salt Reagents; Importance of H/D Exchange Methods in Drug Discovery. ChemMedChem. 2024. 19. 16
Takaaki Aijima, Rina Ueda, Takanori Nakane, Fumiaki Makino, Yusuke Ohnishi, Jin Tokunaga, Keiichiro Nakajima, Shinichiro Kamino, Genji Kurisu, Keiichi Namba, et al. Versatile Biaryls and Fused Aromatics through Oxidative Coupling of Hydroquinones with (Hetero)Arenes. ChemistrySelect. 2024. 9. 15

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MISC (11)：

Yoshinari Sawama. Deuterium-incorporated small molecules; Application to drug discovery and efficient synthesis. 2022. 54. 43-45
Yoshinari Sawama. Synthesis of deuterium-incorporated compounds and progress as deuterium science (Deut-Switch. 2022. 74. 3
Heterogeneously Catalyzed Organic Reactions Using Alcohols as Hydrogen Source. 2017. 59. 1. 15-19
Yoshinari Sawama, Masahiro Masuda, Ryosuke Nakatani, Hiroki Yokoyama, Yasunari Monguchi, Toshifumi Dohi, Yasuyuki Kita, Hironao Sajiki. Front Cover Picture: Site-Selective Iron(III) Chloride-Catalyzed Arylation of 4-Aryl-4-methoxy-2,5-cyclohexadienones for the Synthesis of Polyarylated Phenols (Adv. Synth. Catal. 23/2016). Advanced Synthesis and Catalysis. 2016. 358. 23. 3655
Development of Novel Organic Reactions Based on the Discovery in Total Synthesis of Natural Products. 2014. 65. 4. 256-262

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Patents (39)：

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Books (5)：

Stainless Steel Ball Milling for Hydrogen Generation and its Application for Reduction
有機化学協会誌 2019
アルコールを水素源とした水中で進行する不均一系触媒的環境調和型反応の開発
触媒59巻1号 2017
Environment-Friendly Iron-Catalyzed Reactions
New Horizons of Process Chemistry -Scalable Reactions and Technologies; Tomioka, K., Shioiri, T., Sajiki, H., Eds.; Springer Nature, 2017; pp 51-63. 2017
グリーンサステイナブルな反応開発から水素社会への貢献を目指して
薬事日報 2016
天然物合成に学ぶ新規反応の開発
化学工業 2014

Lectures and oral presentations (12)：

重水素原子置換生体関連物質の網羅的合成と機能性評価
(11th CSJ Chemistry Festa コラボレーション企画特別企画:「重水素学」の今 × 学術変革(B)「革新ラマン」「高分子精密分解」「シナジー創薬学」座談会 2021)
重水素原子置換生体関連物質の網羅的合成と機能性評価
(Deut-Switchキックオフシンポジウム 2021)
重水素標識機能性材料の網羅的合成を目指して
(日本薬学会第141年会 2021)
緩和な条件下での有機化合物への重水素標識化
(重水素化薬剤研究会 2020横浜 2020)
水素抽出型化学変換法の開発と応用展開
(第36回有機合成セミナー 2019)

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Education (1)：

2003 - 2006 Osaka University Graduate School of Pharmaceutical Sciences

Professional career (1)：

博士(薬学) (大阪大学)

Work history (2)：

2021/04 - 現在 Osaka University Graduate School of Pharmaceutical Sciences
2010/02 - 2020/03 Gifu Pharmaceutical University

Awards (4)：

2024/03 - 令和5年度(2023年度)大阪大学沢井記念薬友会(研究部門賞有機分子への重水素導入法の開発と応用
2019/02 - The Society of Synthetic Organic Chemsitry Incentive Award in Synthetic Organic Chemistry Hydrogen Generation from Water, Alkanes, Ether, Alcohols etc. and Its Application to Organic Reactions
2017/12 - 平成29年度(第30回)有機合成化学協会研究企画賞三菱ケミカル脱水素型酸化を基盤とした不均一系触媒的反応の開発と応用
2012 - 有機合成化学協会東海支部奨励賞天然物合成に学ぶ新規反応の開発:ヘテロ環の環開裂型官能基化ならびに官能基選択的還元

Association Membership(s) (4)：

THE JAPANESE SOCIETY FOR PROCESS CHEMISTRY , THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN , THE CHEMICAL SOCIETY OF JAPAN , THE PHARMACEUTICAL SOCIETY OF JAPAN

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