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J-GLOBAL ID：201901000371334616   Update date: Apr. 18, 2024

Yoshinari Sawama

サワマ ヨシナリ | Yoshinari Sawama
Affiliation and department：
Osaka University Graduate School of Pharmaceutical Sciences

About Osaka University Graduate School of Pharmaceutical Sciences


Job title： Associate Professor
Research field  (3)： Green/sustainable/environmental chemistry ,  Synthetic organic chemistry ,  Pharmaceuticals - chemistry and drug development
Research keywords  (5)： 重水素 ,  天然物合成 ,  メカノケミカル ,  不均一系触媒 ,  ルイス酸
Research theme for competitive and other funds  (23)：
  • 2020 - 2024 Development of efficient continuous flow synthesis method using microwave energy accumulation effect
  • 2020 - 2023 Deuterium Science
  • 2021 - 2023 多点反応型不安定中間体の位置選択的官能基化によるビアリール合成と応用
  • 2020 - 2023 Multi-synthesis of deuterium-labelled biological compounds and the evaluation
  • 2020 - 2021 炭類を原料にした人工天然ガス合成法の開発
Show all
Papers (150)：
  • Takaaki Aijima, Rina Ueda, Takanori Nakane, Fumiaki Makino, Yusuke Ohnishi, Jin Tokunaga, Keiichiro Nakajima, Shinichiro Kamino, Genji Kurisu, Keiichi Namba, et al. Versatile Biaryls and Fused Aromatics through Oxidative Coupling of Hydroquinones with (Hetero)Arenes. ChemistrySelect. 2024. 9. 15
  • Kazuho Ban, Shiho Nozaki, Takaaki Aijima, Shuki Oyama, Hirofumi Tsujino, Yusuke Kanematsu, Shuji Akai, Yoshinari Sawama. Furanyl bis(indolyl)methane as a palladium ion-selective chromogenic agent. Organic & biomolecular chemistry. 2024. 22. 14. 2734-2738
  • Takaaki Aijima, Shinsuke Komagawa, Shuji Akai, Yoshinari Sawama. Construction of Functionalized ortho-Naphthoquinone Methides via Site-Selective Ring Opening of 1-Siloxy-1,4-epoxy-1,4-dihydronaphthalenes. Advanced Synthesis & Catalysis. 2023
  • Kazuho Ban, Keisuke Imai, Shuki Oyama, Jin Tokunaga, Yui Ikeda, Hiromasa Uchiyama, Kazunori Kadota, Yuichi Tozuka, Shuji Akai, Yoshinari Sawama. Alkyl Sulfonium Salt-based Reagents for Introduction of Deuterated Alkyl Groups in Drug Discovery. Angewandte Chemie. 2023
  • Shogo Moriyama, Miyu Mae, Daiki Shibata, Hiroyuki Yamakoshi, Shinji Kajimoto, Takakazu Nakabayashi, Takayoshi Ishimoto, Kaiki Mogi, Hironao Sajiki, Shuji Akai, et al. Multiple deuteration of triphenylphosphine and live-cell Raman imaging of deuterium-incorporated Mito-Q. Chemical Communications. 2023. 59. 81. 12100-12103
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MISC (11)：
  • Yoshinari Sawama. Deuterium-incorporated small molecules; Application to drug discovery and efficient synthesis. 2022. 54. 43-45
  • Yoshinari Sawama. Synthesis of deuterium-incorporated compounds and progress as deuterium science (Deut-Switch. 2022. 74. 3
  • Heterogeneously Catalyzed Organic Reactions Using Alcohols as Hydrogen Source. 2017. 59. 1. 15-19
  • Yoshinari Sawama, Masahiro Masuda, Ryosuke Nakatani, Hiroki Yokoyama, Yasunari Monguchi, Toshifumi Dohi, Yasuyuki Kita, Hironao Sajiki. Front Cover Picture: Site-Selective Iron(III) Chloride-Catalyzed Arylation of 4-Aryl-4-methoxy-2,5-cyclohexadienones for the Synthesis of Polyarylated Phenols (Adv. Synth. Catal. 23/2016). Advanced Synthesis and Catalysis. 2016. 358. 23. 3655
  • Development of Novel Organic Reactions Based on the Discovery in Total Synthesis of Natural Products. 2014. 65. 4. 256-262
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Patents (39)：
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Books (5)：
  • Stainless Steel Ball Milling for Hydrogen Generation and its Application for Reduction
    有機化学協会誌 2019
  • アルコールを水素源とした水中で進行する不均一系触媒的環境調和型反応の開発
    触媒59巻1号 2017
  • Environment-Friendly Iron-Catalyzed Reactions
    New Horizons of Process Chemistry -Scalable Reactions and Technologies; Tomioka, K., Shioiri, T., Sajiki, H., Eds.; Springer Nature, 2017; pp 51-63. 2017
  • グリーンサステイナブルな反応開発から水素社会への貢献を目指して
    薬事日報 2016
  • 天然物合成に学ぶ新規反応の開発
    化学工業 2014
Lectures and oral presentations  (12)：
  • 重水素原子置換生体関連物質の 網羅的合成と 機能性評価
    (11th CSJ Chemistry Festa コラボレーション企画特別企画:「重水素学」の今 × 学術変革(B)「革新ラマン」「高分子精密分解」「シナジー創薬学」座談会 2021)
  • 重水素原子置換生体関連物質の 網羅的合成と機能性評価
    (Deut-Switchキックオフシンポジウム 2021)
  • 重水素標識機能性材料の 網羅的合成を目指して
    (日本薬学会第141年会 2021)
  • 緩和な条件下での 有機化合物への重水素標識化
    (重水素化薬剤研究会 2020横浜 2020)
  • 水素抽出型化学変換法の開発と応用展開
    (第36回有機合成セミナー 2019)
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Education (1)：
  • 2003 - 2006 Osaka University Graduate School of Pharmaceutical Sciences
Professional career (1)：
  • 博士(薬学) (大阪大学)
Work history (2)：
  • 2021/04 - 現在 Osaka University Graduate School of Pharmaceutical Sciences
  • 2010/02 - 2020/03 Gifu Pharmaceutical University
Awards (3)：
  • 2019/02 - The Society of Synthetic Organic Chemsitry Incentive Award in Synthetic Organic Chemistry Hydrogen Generation from Water, Alkanes, Ether, Alcohols etc. and Its Application to Organic Reactions
  • 2017/12 - 平成29年度(第30回)有機合成化学協会研究企画賞 三菱ケミカル 脱水素型酸化を基盤とした不均一系触媒的反応の開発と応用
  • 2012 - 有機合成化学協会東海支部奨励賞 天然物合成に学ぶ新規反応の開発:ヘテロ環の環開裂型官能基化ならびに官能基選択的還元
Association Membership(s) (4)：
THE JAPANESE SOCIETY FOR PROCESS CHEMISTRY ,  THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN ,  THE CHEMICAL SOCIETY OF JAPAN ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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