Rchr
J-GLOBAL ID：201201007353202489
Update date: Jul. 14, 2022
Watase Kei
ワタセ ケイ | Watase Kei
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Affiliation and department：
Tokyo Medical and Dental University The Center for Brain Integration Research
About Tokyo Medical and Dental University The Center for Brain Integration Research
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Homepage URL (1)：
http://kaken.nii.ac.jp/ja/r/30376800
Research field (1)：
Neurology
Research keywords (24)：
包括脳ネットワーク
, スプライス
, 脊髄小脳変性症6型
, 神経変性
, ポリグルタミン病
, RNA修復
, 治療
, Q型カルシウムチャネル
, 脊髓小脳変性症
, Caチャンネル
, 動物モデル
, 遺伝子
, 脊髄小脳変性症
, 蛋白質
, 遺伝子治療
, ノックインマウス
, α1A-Caチャンネル
, SCA6
, P
, 培養細胞
, 失調症
, Purkinje細胞
, RNAi
, 神経科学
Papers (30)：
Hiroki Shiwaku, Natsue Yoshimura, Takuya Tamura, Masaki Sone, Soichi Ogishima, Kei Watase, Kazuhiko Tagawa, Hitoshi Okazawa. Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity. EMBO JOURNAL. 2010. 29. 14. 2446-2460
Kei Watase, Kinya Ishikawa, Hidehiro Mizusawa. SCA6: From gene identification to recent progress on pathogenesis. Clinical Neurology. 2010. 50. 11. 858-860
Kei Watase, Curtis F. Barrett, Taisuke Miyazaki, Taro Ishiguro, Kinya Ishikawa, Yuanxin Hu, Toshinori Unno, Yaling Sun, Sayumi Kasai, Masahiko Watainabe, et al. Spinocerebellar ataxia type 6 knockin mice develop a progressive neuronal dysfunction with age-dependent accumulation of mutant Ca(v)2.1 channels. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008. 105. 33. 11987-11992
Jennifer R. Gatchel, Kei Watase, Christina Thaller, James P. Carson, Paymaan Jafar-Nejad, Chad Shaw, Tao Zu, Harry T. Orr, Huda Y. Zoghbi. The insulin-like growth factor pathway is altered in spinocerebellar ataxia type 1 and type 7. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2008. 105. 4. 1291-1296
Okiru Komine, Mai Nagaoka, Kei Watase, David H. Gutmann, Kenji Tanigaki, Tasuku Honjo, Freddy Radtke, Toshiki Saito, Shigeru Chiba, Kohichi Tanaka. The monolayer formation of Bergmann glial cells is regulated by Notch/RBP-J signaling. DEVELOPMENTAL BIOLOGY. 2007. 311. 1. 238-250
ｍore...
Lectures and oral presentations (1)：
SCA6 -原因の同定から治療法の開発へ-
(第51回日本神経学会総会 2010)
Work history (1)：
2008/05 - 2012 Tokyo Medical and Dental University
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