Art

J-GLOBAL ID：201902239398441264   Reference number：19A0980950

Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice

TLR2とMinCleによる連続センシングはマウスにおける侵入性A群連鎖球菌感染を防御するために未成熟骨髄細胞を指示する【JST・京大機械翻訳】

Author (28)： Matsumura Takayuki (Department of Immunology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan) ,  Ikebe Tadayoshi (Department of Bacteriology I, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan) ,  Arikawa Koji (Research Organization for Nano and Life Innovation, Waseda University, 513 Waseda-tsurumaki-cho, Shinjuku-ku, Tokyo 162-0041, Japan) ,  Arikawa Koji (Computational Bio Big-Data Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology, 3-4-1 Okubo, Shinjuku-ku, Tokyo 169-8555, Japan) ,  Hosokawa Masahito (Research Organization for Nano and Life Innovation, Waseda University, 513 Waseda-tsurumaki-cho, Shinjuku-ku, Tokyo 162-0041, Japan) ,  Hosokawa Masahito (Institute for Advanced Research of Biosystem Dynamics, Waseda Research Institute for Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan) ,  Aiko Michio (Department of Immunology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan) ,  Iguchi Aoi (Department of Immunology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan) ,  Iguchi Aoi (Tokyo College of Biotechnology, 1-3-14 Kita-Kojiya, Ota-ku, Tokyo 144-0032, Japan) ,  Togashi Ikuko (Department of Immunology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan) ,  Togashi Ikuko (Tokyo College of Biotechnology, 1-3-14 Kita-Kojiya, Ota-ku, Tokyo 144-0032, Japan) ,  Kai Sayaka (Department of Immunology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan) ,  Kai Sayaka (Dental School, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama-shi, Okayama 700-8558, Japan) ,  Ohara Sakiko (Department of Immunology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan) ,  Ohara Sakiko (Dental School, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama-shi, Okayama 700-8558, Japan) ,  Ohara Naoya (Dental School, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama-shi, Okayama 700-8558, Japan) ,  Ohara Naoya (Department of Oral Microbiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama-shi, Okayama 700-8558, Japan) ,  Ohnishi Makoto (Department of Bacteriology I, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan) ,  Watanabe Haruo (School of Medicine, International University of Health and Welfare, 4-3 Kozunomori, Narita-shi, Chiba 286-8686, Japan) ,  Kobayashi Kazuo (Division of Public Health, Osaka Institute of Public Health, 1-3-69 Nakamichi, Higashinari-ku, Osaka-shi, Osaka 537-0025, Japan) ,  Takeyama Haruko (Research Organization for Nano and Life Innovation, Waseda University, 513 Waseda-tsurumaki-cho, Shinjuku-ku, Tokyo 162-0041, Japan) ,  Takeyama Haruko (Computational Bio Big-Data Open Innovation Laboratory, National Institute of Advanced Industrial Science and Technology, 3-4-1 Okubo, Shinjuku-ku, Tokyo 169-8555, Japan) ,  Takeyama Haruko (Institute for Advanced Research of Biosystem Dynamics, Waseda Research Institute for Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan) ,  Takeyama Haruko (Department of Life Science and Medical Bioscience, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan) ,  Yamasaki Sho (Division of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita-shi, Osaka 565-0871, Japan) ,  Yamasaki Sho (Division of Molecular Immunology, Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita-shi, Osaka 565-0871, Japan) ,  Takahashi Yoshimasa (Department of Immunology, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan) ,  Ato Manabu (Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, 4-2-1 Aoba-cho, Higashimurayama-shi, Tokyo 189-0002, Japan)
Material： Cell Reports
Volume： 27  Issue： 2  Page： 561-571.e6  Publication year： 2019 
JST Material Number： W3124A  ISSN： 2211-1247  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Severe invasive group A Strept...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=19A0980950&from=J-GLOBAL&jstjournalNo=W3124A") }}

Thesaurus term： macrophage ,  interleukin 6 ,  immersional wetting ,  Toll like receptor ,  *mouse(animal) ,  paracrine ,  *myeloid cell ,  up-regulation ,  interferon gamma ,  cell component ,  natural immunity
Semi thesaurus term： *Mincle ,  *未成熟 ,  *Toll様受容体2 , 【Automatic Indexing@JST】

Author keywords (5)： group A Streptococcus infections ,  immature myeloid cells ,  Toll-like receptors ,  C-type lectin receptors ,  cytokines

JST classification (5)： Cell physiology in general  (EF02010S) ,  Infectious immunity  (ED03030P) ,  Gene expression  (EC02040Q) ,  Immunological reaction in general  (ED03010T) ,  Molecular genetics in general  (EC02010J)

Terms in the title (10)： TLR2 ,  Mincle ,  センシング ,  マウス ,  侵入 ,  A群連鎖球菌 ,  感染 ,  防御 ,  成熟 ,  骨髄細胞