Rchr

J-GLOBAL ID：200901075539105050 Update date: Jan. 30, 2024

Moriwaki Hisataka

モリワキヒサタカ | Moriwaki Hisataka

Affiliation and department：

Research field (3)： Gastroenterology , Hematology and oncology , Gastroenterology

Research keywords (6)： Cancer Studies , Hepatology , Gastroenterology , がん研究 , 肝臓病学 , 消化器病学

Research theme for competitive and other funds (33)：

2013 - 2016 Elucidation of new target molecules preventing obesity-related liver carcinogenesis
2010 - 2016 Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
2013 - 2015 レチノイド核内受容体RXRα遺伝子改変マウスを用いた肝発癌機序の解析
2011 - 2013 Development of Quality Improvement Method for the Best Clinical Process Using Next-Generation Electronic Medical Record System
2009 - 2011 Combination chemoprevention of hepatocellular carcinoma with acyclic retinoid by targeting RXRαphosphorylation

2008 - 2010 Development of Analyzing Tool for the Best Clinical Cancer Process Using Next-Generation Electronic Medical Record System

2005 - 2009 核内受容体蛋白を分子標的とした肝癌化学予防に関する研究

2007 - 2008 Strategy for chemoprevention of digestive cancers by targeting abnormalities in receptor tyrosine kinases and nuclear receptors

2005 - 2007 The study of anti-hepatitis B virus drugs using RNA technology

2004 - 2006 RECEPTOR DYSFUNCTION AND CANCER CHEMOPREVENTION BY RETINOID AND INTERFERON

2004 - 2006 サイトカイン連鎖による肝再生不全発症機序の解明とその制御による治療法の開発

2006 - 難治性の肝・胆道疾患に関する調査研究

2006 - 肝がん患者のQOL向上に関する研究

2003 - 2005 The Role of the Tumor Necrosis Factor Receptor in 2,4,6-Trinitrobenzene Sulphonic Acid (TNBS)-induced Colitis in Mice

2005 - 難治性の肝・胆道疾患に関する調査研究

2002 - 2004 APOPTOSIS BY THE INHIBITION OF TELOMERASE ACTIVITY IN CANCER CELLS

2001 - 2004 核受容体蛋白を標的分子としたがん化学予防の研究

2001 - 2003 レチノイドによるサイトカイン受容体発現調節を介した癌細胞サイトカイン感受性の制御

2003 - 末期肝硬変に対する治療に関する研究

2003 - 難治性の肝疾患

2003 - 肝がん患者のQOL向上に関する研究

2000 - 2002 MODIFICATION OF GROWTH AND APOPTOSIS BY UBIQUITINATION IN HEPATOMA CELL

1999 - 2001 REGULATION OF HEPATOCARCINOGENESIS BY ACYCLIC RETINOID

1998 - 2000 DEVELOPMENT OF BIOARTIFICIAL LIVER

1998 - 2000 MECHANISMS OF CLONAL DELETION OF HEPATOCELLULAR CARCINOMA BY ACYCLICRETINOID

1996 - 1998 MECHANISMS OF REGULATION AND CONTROL OF HEPATOCARCINOGENESIS BY ACYCLIC RETINOID

1994 - 1996 Inhibition of Liver Fibrosis by Retinoid Antagonist

1994 - 1996 Clinical and experimental studies on protein metabolism in acute hepatic failure-with special relation to effects of branched-chain amino acid infusion

1993 - 1995 GENOMIC MECHANISMS OF REGULATION AND CONTROL OF HEPATOCARCINOGENESIS BY RETINOIDS

Regulation and prevention of carcinogenesis

Pathobiology and treatment of hepatic failure

発癌の制御・予防

肝不全の病態と治療

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Papers (714)：

Tatsunori Hanai, Makoto Shiraki, Kenji Imai, Atsushi Suetsugu, Koji Takai, Hisataka Moriwaki, Masahito Shimizu. Reduced handgrip strength is predictive of poor survival among patients with liver cirrhosis: A sex-stratified analysis. Hepatology research : the official journal of the Japan Society of Hepatology. 2019. 49. 12. 1414-1426
Ryuta Shigefuku, Motoh Iwasa, Kazuhiro Katayama, Akiko Eguchi, Takumi Kawaguchi, Koichi Shiraishi, Toshifumi Ito, Kazutomo Suzuki, Chizu Koreeda, Takaaki Ohtake, et al. Hypozincemia is associated with human hepatocarcinogenesis in hepatitis C virus-related liver cirrhosis. Hepatology Research. 2019. 49. 10. 1127-1135
Tatsunori Hanai, Makoto Shiraki, Satoshi Watanabe, Kenji Imai, Atsushi Suetsugu, Koji Takai, Hisataka Moriwaki, Masahito Shimizu. Prognostic significance of minimal hepatic encephalopathy in patients with liver cirrhosis in Japan: A propensity score-matching analysis. Journal of gastroenterology and hepatology. 2019. 34. 10. 1809-1816
岩佐元雄, 片山和宏, 白石光一, 伊藤敏文, 鈴木壱知, 是枝ちづ, 大竹孝明, 徳本良雄, 遠藤龍人, 川村直弘, et al. C型肝硬変において低亜鉛血症は肝発癌を促進する. 日本病態栄養学会誌. 2019. 22. Suppl. S-70
Tatsunori Hanai, Makoto Shiraki, Takao Miwa, Satoshi Watanabe, Kenji Imai, Atsushi Suetsugu, Koji Takai, Hisataka Moriwaki, Masahito Shimizu. Effect of loop diuretics on skeletal muscle depletion in patients with liver cirrhosis. Hepatology research : the official journal of the Japan Society of Hepatology. 2019. 49. 1. 82-95

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MISC (882)：

Xian-Yang Qin, Harukazu Suzuki, Masao Honda, Hikari Okada, Shuichi Kaneko, Ikuyo Inoue, Etsuko Ebisui, Kosuke Hashimoto, Piero Carninci, Keita Kanki, et al. Prevention of hepatocellular carcinoma by targeting MYCN-positive liver cancer stem cells with acyclic retinoid. Proceedings of the National Academy of Sciences of the United States of America. 2018. 115. 19. 4969-4974
Sachiyo Onishi, Makoto Shiraki, Kayoko Nishimura, Tatsunori Hanai, Hisataka Moriwaki, Masahito Shimizu. Prevalence of Sarcopenia and Its Relationship with Nutritional State and Quality of Life in Patients with Digestive Diseases. Journal of nutritional science and vitaminology. 2018. 64. 6. 445-453
Tatsunori Hanai, Makoto Shiraki, Satoshi Watanabe, Takahiro Kochi, Kenji Imai, Atsushi Suetsugu, Koji Takai, Hisataka Moriwaki, Masahito Shimizu. Sarcopenia predicts minimal hepatic encephalopathy in patients with liver cirrhosis. Hepatology research : the official journal of the Japan Society of Hepatology. 2017. 47. 13. 1359-1367
Soichi Kojima, Xian-Yang Qin, Sanae Sekihara, Akimori Wada, Naoto Ishibashi, Hisataka Moriwaki, Masahito Shimizu. Mechanisms of Selective Deletion of MYCN(+)CD133(+) Liver Cancer Stem Cells by Acyclic Retinoid via Induction of Nuclear Transglutaminase 2. HEPATOLOGY. 2017. 66. 985A-985A
Takuji Tanaka, Takahiro Kochi, Yohei Shirakami, Takayuki Mori, Ayumi Niwa, Naoki Watanabe, Hisataka Moriwaki, Masahito Shimizu. Cimetidine and Clobenpropit Attenuate Inflammation-Associated Colorectal Carcinogenesis in Male ICR Mice (vol 8, 25, 2016). CANCERS. 2017. 9. 7

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Patents (3)：

酸化型アルブミン低下剤
酸化型アルブミン低下剤
OXIDATIONTYPEALBUMIN-REDUCINGAGENT

Lectures and oral presentations (203)：

非アルコール性脂肪性肝疾患におけるhedgehogを介した上皮細胞-間葉細胞移行と線維性損傷修復
(2010)
特集「胆膵EUS-FNAのエビデンス2010」EUSガイド下腹腔神経叢
(2010)
特集「やっぱり大切、基本手技」
(2010)
特集「Stenting Bible」胆管狭窄に対するStenting Strategy:良性狭窄 Coverd Metallic Stentを用いた治療
(2010)
特集「Stenting Bible」胆管狭窄に対するStenting Strategy:悪性肝門部胆管狭窄各種ステントの選択-PlasticかMetalか-
(2010)

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Education (2)：

1970 - 1976 Gifu University School of Medicine
- 1976 Gifu University Faculty of Medicine

Professional career (1)：

(BLANK) (Gifu University)

Work history (1)：

1984/04/01 - 2011/03/31 Gifu University Graduate School of Medicine

Committee career (5)：

1993 - 2001 日本肝臓学会評議員
1998 - 1999 日本内科学会評議員
1994 - 1999 日本ビタミン学会評議員,幹事
1992 - 1999 日本消化器病学会評議員
1991 - 1999 日本臨床代謝学会評議員

Awards (3)：

1998 - 日本肝臓学会賞(織田賞)
1989 - 東海学術奨励賞
1989 - 日本肝臓学会奨励賞

Association Membership(s) (9)：

日本老年医学会 , 日本血液学会 , 日本臨床代謝学会 , 日本癌学会 , 日本ビタミン学会 , 日本消化器内視鏡学会 , 日本肝臓学会 , 日本消化器病学会 , 日本内科学会

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